Effects of Current Size, Postnatal Growth, and Birth Size on Blood Pressure in Early Childhood
| Autor: | Sinead Bryan, Michael Geary, Tim J Cole, Peter C. Hindmarsh |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
Gestational hypertension Pediatrics medicine.medical_specialty Birth weight Physiology Blood Pressure Weight Gain Essential hypertension Risk Factors Birth Weight Humans Medicine Prospective Studies Family history Prospective cohort study business.industry Infant Newborn Infant medicine.disease United Kingdom Blood pressure Child Preschool Hypertension Pediatrics Perinatology and Child Health Female medicine.symptom business Weight gain Body mass index Follow-Up Studies |
| Zdroj: | Pediatrics. 126:e1507-e1513 |
| ISSN: | 1098-4275 0031-4005 |
| DOI: | 10.1542/peds.2010-0358 |
| Popis: | OBJECTIVE: In a prospective study, we investigated the impact of early growth on blood pressure at 3 years of age. METHODS: We measured systolic blood pressure (SBP) and diastolic blood pressure (DBP) for 590 children 3 years of age and related measurements to current size and size at birth, 6 months, 1 year, and 2 years of age. RESULTS: SBP was related positively to weight at 3 and 2 years and, after adjustment for current size, negatively to weight at birth and 6 months but not at 1 or 2 years. No effect was observed for DBP. A family history of hypertension was associated with higher maternal blood pressure, greater weight, and gestational hypertension (P = .05). Mothers with a history of gestational hypertension had higher SBP and DBP values (P < .001). In multivariate linear regression analyses, SBP was influenced positively by weight at 3 years and family history of hypertension and negatively by weight at 6 months. None of the factors was associated with DBP. CONCLUSIONS: For 3-year-old children, current weight was a determinant of SBP and postnatal growth to 6 months of age was more predictive than birth weight. A family history of hypertension is important in determining maternal blood pressure. These observations suggest a window in which postnatal growth might be modified. |
| Databáze: | OpenAIRE |
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