0165 : Evaluation of the lipid profile in the cardiovascular risk in patients with systemic lupus erythematosus
| Autor: | Adolphe Kasongo, Rachida Habbal, Hafdi Karim, Abdelaziz Hadadi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Cholesterol Hypertriglyceridemia Lupus nephritis Disease medicine.disease Obesity chemistry.chemical_compound chemistry Internal medicine Physical therapy Medicine In patient business Prospective cohort study Lipid profile Cardiology and Cardiovascular Medicine |
| Zdroj: | Archives of Cardiovascular Diseases Supplements. 8(3) |
| ISSN: | 1878-6480 |
| DOI: | 10.1016/s1878-6480(16)30373-1 |
| Popis: | Introduction the occurrence of early atherosclerosis in systemic lupus erythematosus is currently established; both groups of factors are implicated: classical risk factors and disease -specific factors (age, activity and treatment). Today cardiovascular mortality is the leading cause of mortality in SLE patients. Objective To evaluate the frequency of hypercholesterolemia; the hypoHDL – cholesterol and / or hypertriglyceridemia in SLE patients, and its relationship with cardiovascular events and other serious clinical manifestations (lupus nephritis, neurological damage ...). Methods Prospective study spread over 1 year including 58 patients with SLE followed in consultation or hospitalization in internal medicine and cardiology departments of UH Ibn Rochd of Casablanca. The study parameters are: age, sex; cardiovascular risk factors, lipid profile, clinical assessment and treatment of the disease. Results our patients are divided into 52 women and 6 men, age means is 34.42 years with a range of [16-61 years], the average duration of disease evolution is 2 years. Age as cardiovascular risk factors is reported in 2 patients, male gender in 6 cases, and obesity in 5 cases. Hypercholesterolemia was found in 3 patients; hypertriglyceridemia in 6 patients; 11 patients have hypoHDL – Lemie. The thickness intima / media evaluated in 19 patients was normal ( Conclusion first results show that patients who have a disturbed lipid profile are those who develop more cardiovascular events, hence the need to continue this study and to recruit more patients to assess the immunosuppressive effects on cardiovascular risk in SLE patients. The author hereby declares no conflict of interest |
| Databáze: | OpenAIRE |
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