'Blueberry muffin' rash and large right thigh mass: a unique presentation of Langerhans cell histiocytosis
| Autor: | Rebecca Moran, Robert Quinn, Aimee C. Smidt, Shelly Stepenaskie, Erica G Lau, Prasad Matthew |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Pathology medicine.medical_specialty Biopsy Dermatology Thigh Vinblastine Langerhans cell histiocytosis Medicine Humans Right Thigh Skin medicine.diagnostic_test business.industry Infant Newborn Soft tissue Calcinosis General Medicine Exanthema medicine.disease Rash Magnetic Resonance Imaging Histiocytosis Histiocytosis Langerhans-Cell medicine.anatomical_structure blueberry muffin rash Hematopoiesis Extramedullary Prednisone Drug Therapy Combination Bone marrow medicine.symptom business |
| Zdroj: | Lau, Erica G; Stepenaskie, Shelly; Moran, Rebecca; Quinn, Robert; Matthew, Prasad; & Smidt, Aimee C. (2013). “Blueberry muffin” rash and large right thigh mass: a unique presentation of Langerhans cell histiocytosis. Dermatology Online Journal, 19(6). Retrieved from: http://www.escholarship.org/uc/item/3px1976v |
| ISSN: | 1087-2108 |
| Popis: | Langerhans cell histiocytosis (LCH) is a clonal proliferation of bone marrow derived antigen-presenting cells that can involve a spectrum of cutaneous findings, with or without internal organ involvement. Neonatal LCH almost always presents with skin findings, usually petechial papules and/or erosions in a seborrheic distribution, with or without extracutaneous involvement. Previously described as varying entities, LCH is now considered a single disease process demonstrating a spectrum of clinical findings. We report a unique case of neonatal LCH presenting with a “blueberry muffin” rash in conjunction with a large soft tissue tumor. |
| Databáze: | OpenAIRE |
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