How predictive is the MMSE for cognitive performance after stroke?
| Autor: | Sascha M.C. Rasquin, Ariane Bour, Frans R.J. Verhey, Martien Limburg, Anita Boreas |
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| Přispěvatelé: | Revalidatiegeneeskunde, Klinische Neurowetenschappen, Psychiatrie & Neuropsychologie, MUMC+: MA Med Staf Spec Psychiatrie (9), MUMC+: HZC Klinische Neurofysiologie (5), RS: CAPHRI School for Public Health and Primary Care, RS: MHeNs School for Mental Health and Neuroscience |
| Jazyk: | angličtina |
| Předmět: |
Male
medicine.medical_specialty Neurology Time Factors Clinical Neurology Neuropsychological Tests MMSE Physical medicine and rehabilitation Cognition Memory Predictive Value of Tests medicine Dementia Humans Attention Cognitive skill Effects of sleep deprivation on cognitive performance Psychiatry Stroke Aged Language Retrospective Studies Aged 80 and over Original Communication medicine.diagnostic_test Neuropsychological test Middle Aged medicine.disease ROC Curve Predictive value of tests Visual Perception Female Neurology (clinical) Psychology Cognition Disorders Mental Status Schedule Follow-Up Studies |
| Zdroj: | Journal of Neurology, 257(4), 630-637. Springer Journal of Neurology |
| ISSN: | 0340-5354 |
| DOI: | 10.1007/s00415-009-5387-9 |
| Popis: | Cognitive deficits are commonly observed in stroke patients. Neuropsychological testing is time-consuming and not easy to administer after hospital discharge. Standardised screening measures are desirable. The Mini-Mental State Examination (MMSE) is the test most widely applied to screen for cognitive deficits. Despite its broad use, its predictive characteristics after stroke have not been exhaustively investigated. The aim of this study was to determine whether the MMSE is able to adequately screen for cognitive impairment and dementia after stroke and whether or not the MMSE can predict further deterioration or recovery in cognitive function over time. To this end, we studied 194 first-ever stroke patients without pre-stroke cognitive deterioration who underwent MMSEs and neuropsychological test batteries at 1, 6, 12, and 24 months after stroke. The MMSE score 1 month after stroke predicted cognitive functioning at later follow-up visits. It could not predict deterioration or improvement in cognitive functioning over time. The cut-off score in the screening for 1 cognitive disturbed domain was 27/28 with a sensitivity of 0.72. The cut-off score in the screening for at least 4 impaired domains and dementia were 26/27 and 23/24 with a sensitivity of 0.82 and 0.96, respectively. The results indicated that the MMSE has modest qualities in screening for mild cognitive disturbances and is adequate in screening for moderate cognitive deficits or dementia in stroke patients 1 month after stroke. Poor performance on the MMSE is predictive for cognitive impairment in the long term. However, it cannot be used to predict further cognitive deterioration or improvement over time. |
| Databáze: | OpenAIRE |
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