The global impact of vaccines containing aluminium adjuvants
| Autor: | C. J. Clements, Elwyn Griffiths |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Pertussis Vaccine
Vaccines General Veterinary General Immunology and Microbiology business.industry Diphtheria Toxoid Immunization Programs Public Health Environmental and Occupational Health Infant Newborn Infectious Diseases Risk analysis (engineering) Immunization Adjuvants Immunologic Immunology Tetanus Toxoid Molecular Medicine Medicine Humans Hepatitis B Vaccines business Aluminum |
| Zdroj: | Vaccine. 20 |
| ISSN: | 0264-410X |
| Popis: | Immunization against childhood vaccine-preventable diseases has arguably had the greatest impact on the health of children of any public health intervention. Many of the vaccines used in the Expanded Programme on Immunization (EPI) have contained aluminium-based adjuvants. As such, these adjuvants have played a vital role in enabling the basic vaccines to be used effectively. DTP global supply is fragile and could easily be upset through the loss of even one major vaccine manufacturer. Non-aluminium adjuvants could not readily replace aluminium adjuvants. New generation vaccines will probably need new generation adjuvants. The impact of vaccines with adjuvants is discussed. Having provided decades of reliable, safe service in their relatively simple chemical formulations, adjuvants are likely to be with us, in one form or another, for the indefinite future. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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