Use of Ramelteon for the Treatment of Secondary REM Sleep Behavior Disorder
| Autor: | Shinya Kawase, Kenji Nakashima, Takashi Nomura, Yasuhiro Watanabe |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Male
Parkinson's disease Polysomnography Ramelteon Receptors Melatonin REM Sleep Behavior Disorder REM sleep behavior disorder Non-rapid eye movement sleep Clonazepam Sleep Apnea Syndromes Atrophy Internal Medicine medicine Humans Adverse effect Aged medicine.diagnostic_test business.industry musculoskeletal neural and ocular physiology Parkinson Disease General Medicine Middle Aged Multiple System Atrophy medicine.disease Indenes Anesthesia Female business medicine.drug |
| Zdroj: | Internal Medicine. 52:2123-2126 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.52.9179 |
| Popis: | We used ramelteon to treat two patients with secondary REM sleep behavior disorder (RBD) complications along with neurodegenerative diseases including multiple system atrophy and Parkinson's disease. These two patients not only improved in terms of their clinical RBD symptoms but also exhibited a decrease in the proportion of REM sleep without atonia (from 8.5% to 3.5% and from 10.9% to 3.9% in the two patients). Although clonazepam is the standard first-line therapy for the treatment of RBD, ramelteon might be an effective treatment alternative in patients with RBD who cannot take clonazepam due to either ineffectiveness or adverse effects. |
| Databáze: | OpenAIRE |
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