Progressive increases in creatine kinase activity in an anorexic cat with necrotising myopathy
| Autor: | Amy Lam, G. Diane Shelton, Joyce Ly Chow |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Myopathy Veterinary medicine Case Report necrotising myopathy 03 medical and health sciences 0302 clinical medicine Weight loss Internal medicine SF600-1100 medicine Small Animals 030203 arthritis & rheumatology biology creatine kinase business.industry muscle degeneration Muscle degeneration Reduced appetite Endocrinology myonecrosis biology.protein Creatine kinase medicine.symptom business Creatine kinase activity 030217 neurology & neurosurgery |
| Zdroj: | Journal of Feline Medicine and Surgery Open Reports, Vol 7 (2021) JFMS Open Reports |
| ISSN: | 2055-1169 |
| Popis: | Case summary A 5-year-old castrated male domestic shorthair cat with weight loss and reduced appetite was evaluated for increased and progressively rising creatine kinase (CK) activity. The cat had recently been diagnosed with hepatic lipidosis. Muscle biopsy and histopathology revealed mild myonecrosis and phagocytosis without obvious inflammatory cell infiltrates. Resolution of necrotising myopathy was observed after a short course of anti-inflammatory prednisolone and nutritional supplementation. Relevance and novel information This is the first report of a necrotising myopathy in a cat associated with progressively increasing CK activity and decreased appetite. Anorexia in cats has been associated with increased CK activity, but an underlying cause of this CK elevation has only been postulated. Here we document muscle necrosis and muscle stiffness in a cat with anorexia. |
| Databáze: | OpenAIRE |
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