Feeding preterm neonates with patent ductus arteriosus (PDA): intestinal blood flow characteristics and clinical outcomes
| Autor: | Thomas Havranek, Eric S. Armbrecht, Mohammad Dawood Rahimi, Heather L. Hall |
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| Rok vydání: | 2014 |
| Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities education Infant Premature Diseases Enteral administration Enteral Nutrition Bolus (medicine) Patent ductus arteriosus (PDA) Ductus arteriosus medicine.artery medicine Humans Superior mesenteric artery Infant Nutritional Physiological Phenomena Ductus Arteriosus Patent business.industry Hemodynamics Infant Newborn Obstetrics and Gynecology Left pulmonary artery Prognosis medicine.disease Intestines Low birth weight medicine.anatomical_structure Postprandial Regional Blood Flow Anesthesia Pediatrics Perinatology and Child Health Female medicine.symptom business Blood Flow Velocity Infant Premature |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 28:526-530 |
| ISSN: | 1476-4954 1476-7058 |
| Popis: | To evaluate the effects of patent ductus arteriosus (PDA) on postprandial superior mesenteric artery blood flow velocities (SMA BFV)s and feeding tolerance in extremely low birth weight (ELBW) neonates.Appropriate for gestational age, ELBW preterm neonates, tolerating bolus enteral feedings were eligible to participate in this prospective observational study. Pulsed Doppler was used to measure preprandial and postprandial (at 30 and 60 min) time-averaged mean velocity (TAMV), peak systolic velocity (PSV) and end diastolic velocity (EDV) once during the day of life 5-7; at the same time, PDA size was estimated using the PDA: left pulmonary artery (LPA) ratio.A total of 38 infants were studied, 16 in small, 13 in moderate and 9 in large PDA groups. The postprandial SMA BFVs were lower in the large PDA group, although not reaching statistical significance. Importantly, infants in the large PDA group reached full enteral intake later (p = 0.02) and had higher incidence of death secondary of necrotizing enterocolitis (NEC; p = 0.04).ELBW preterm neonates with large PDA may have attenuated intestinal blood flow responses to feedings. There was also an association with higher rates of necrotizing enterocolitis and feeding intolerance in the large PDA group. |
| Databáze: | OpenAIRE |
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