Hair cell degeneration in guinea pigs intoxicated with kanamycin during intrauterine life

Autor: R Romand, J Gabrion, Alain Uziel
Rok vydání: 1979
Předmět:
Zdroj: Archives of Oto-Rhino-Laryngology. 224:187-191
ISSN: 1434-4726
0302-9530
DOI: 10.1007/bf01108777
Popis: The structural ototoxic effect of kanamycin during intrauterine life has been shown in guinea pigs. The extent of the loss mostly affected the outer hair cells of the basal part of the cochlea. Ultrastructural studies demonstrated a hair cell degeneration pattern similar to that previously described in adult animals following antibiotic intoxication.
Databáze: OpenAIRE