Need for Vitreous Surgeries in Proliferative Diabetic Retinopathy in 10-Year Follow-Up: India Retinal Disease Study Group Report No. 2

Autor: Rehana Khan, Rajiv Raman, Gajendra Chawla, Vinata Muralidharan, Lanin Chen, Sundaram Natarajan, Abhishek Desai, Ramachandran Rajalakshmi, Mahesh Gopalakrishnan, Janani Surya, Giridhar Anantharaman, Lingam Gopal, Padmaja Kumari Rani, Sobha Sivaprasad, Alok Sen, Umesh Chandra Behera, Rupak Roy
Rok vydání: 2020
Předmět:
Zdroj: Ophthalmic Research. 64:432-439
ISSN: 1423-0259
0030-3747
DOI: 10.1159/000512767
Popis: Introduction: To report the 10-year rate of vitrectomies and the associated factors in people with proliferative diabetic retinopathy (PDR) from a multicentric cohort of people with diabetes mellitus. Methods: Ten centres in India with established vitreoretinal (VR) services for over 10 years were invited to provide long-term data on PDR. People with Type 1 or 2 diabetes with a clinical diagnosis of active PDR in 1 or both eyes were included. Baseline data collected included age, sex, duration of diabetes, source of referral and best-corrected visual acuity, and diabetic retinopathy status in both eyes. Available follow-up data included the numbers of panretinal photocoagulation (PRP) sessions, cataract surgery, treatment of diabetic macular oedema, use of anti-vascular endothelial growth factor (VEGF) therapy, vitrectomy with or without retinal surgeries over 10 years. Results: Over 10 years, 89% needed supplemental PRP after initial complete PRP. One-third required retinal surgery, 16% needed intravitreal injection. Men (74.5%) had significant higher risk for vitreous (VR) surgery. Of the group with low-risk PDR, 56.8% did not require VR surgery, p < 0.001. Of the patients who underwent cataract surgery and had intravitreal anti-VEGF injections, 78.5 and 28.2% needed subsequent vitreous (VR) surgery, p = 0.006 and
Databáze: OpenAIRE