Effectiveness of infection prevention and control interventions, excluding personal protective equipment, to prevent nosocomial transmission of SARS-CoV-2: a systematic review and call for action
| Autor: | Rachel Lowe, Stéphane Hué, Katherine E. Atkins, C. Julian Villabona-Arenas, Rosalind M Eggo, W. John Edmunds, Christopher I Jarvis, Samuel Clifford, Adam J. Kucharski, Kerry Lm. Wong, Frank Sandmann, Sam Abbott, Nikos I Bosse, Yang Liu, Cherry Lim, Gwenan M. Knight, Hamish Gibbs, Fiona Yueqian Sun, Rosanna C. Barnard, Damien C. Tully, Matthew Quaife, Carl A. B. Pearson, Emilie Finch, Timothy W Russell, Kaja Abbas, Paul Mee, Jonathan M Read, Yalda Jafari, Lloyd A.C. Chapman, Simon R Procter, Rachael Pung, Mo Yin, Mark Jit, Sebastian Funk, Graham F. Medley, Oliver J. Brady, Kiesha Prem, Ciara V. McCarthy, Sophie Meakin, James D Munday, Stefan Flasche, Akira Endo, William Waites, Nicholas G Davies, James Stimson, Billy J Quilty, David Hodgson, Mihaly Koltai, Alicia Rosello, Joel Hellewell, Ben S. Cooper, Julie V. Robotham, Stephanie Evans, Katharine Sherratt, Kathleen M. O’Reilly, Diane Pople, Amy Gimma, Thi Mui Pham |
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| Přispěvatelé: | group, LSHTM CMMID COVID-19 working |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Isolation (health care) business.industry Control (management) Public Health Environmental and Occupational Health Psychological intervention Infectious and parasitic diseases RC109-216 Article Infectious Diseases Action (philosophy) Intervention (counseling) Health care medicine Infection control Public aspects of medicine RA1-1270 Intensive care medicine business Personal protective equipment |
| Zdroj: | Infection Prevention in Practice Infection Prevention in Practice, Vol 4, Iss 1, Pp 100192-(2022) |
| ISSN: | 2590-0889 |
| Popis: | Summary Many infection prevention and control (IPC) interventions have been adopted by hospitals to limit nosocomial transmission of SARS-CoV-2. The aim of this systematic review is to identify evidence on the effectiveness of these interventions. We conducted a literature search of five databases (OVID MEDLINE, Embase, CENTRAL, COVID-19 Portfolio(pre-print), Web of Science). SWIFT ActiveScreener software was used to screen English titles and abstracts published between 1st January 2020 and 6th April 2021. Intervention studies, defined by Cochrane Effective Practice and Organisation of Care, that evaluated IPC interventions with an outcome of SARS-CoV-2 infection in either patients or healthcare workers were included. Personal protective equipment (PPE) was excluded as this intervention had been previously reviewed. Risks of bias were assessed using the Cochrane tool for randomised trials (RoB2) and non-randomized studies of interventions (ROBINS-I). From 23,156 screened articles, we identified seven articles that met the inclusion criteria, all of which evaluated interventions to prevent infections in healthcare workers and the majority of which were focused on effectiveness of prophylaxes. Due to heterogeneity in interventions, we did not conduct a meta-analysis. All agents used for prophylaxes have little to no evidence of effectiveness against SARS-CoV-2 infections. We did not find any studies evaluating the effectiveness of interventions including but not limited to screening, isolation and improved ventilation. There is limited evidence from interventional studies, excluding PPE, evaluating IPC measures for SARS-CoV-2. This review calls for urgent action to implement such studies to inform policies to protect our most vulnerable populations and healthcare workers. |
| Databáze: | OpenAIRE |
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