Dermatomyositis Flare With Immune Checkpoint Inhibitor Therapy for Melanoma
| Autor: | Rachel Thomas, Joshua Scott, Hamish Patel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Metastatic melanoma dermatomyositis Immune checkpoint inhibitors Dermatology 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Rheumatology Internal medicine medicine myositis flare Adverse effect Myositis nivolumab business.industry Melanoma General Engineering immune-related adverse effects Dermatomyositis medicine.disease immune checkpoint inhibitors (icis) Nivolumab business myositis 030217 neurology & neurosurgery metastatic melanoma |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Immune checkpoint inhibitor (ICI) medications have seen expanded use in the management of numerous malignancies. These therapies encompass a unique spectrum of immune-related adverse events (irAEs). Rheumatological irAEs from ICIs have been described in various case reports; however, limited literature exists regarding the treatment of patients with pre-existing myositis. We describe a case of myositis flare after initiation of nivolumab for metastatic melanoma in a patient who had previously achieved remission of dermatomyositis. |
| Databáze: | OpenAIRE |
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