The effect of intravenous tenoxicam on pruritus in patients receiving epidural fentanyl
| Autor: | Deirdre M O’Hanlon, Frank Chambers, D. C. Moriarty, Sallyann Colbert |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty Analgesic Fentanyl Piroxicam Bolus (medicine) Tenoxicam Abdomen Medicine Humans Cyclooxygenase Inhibitors Prospective Studies Prospective cohort study Aged Pain Postoperative business.industry Pruritus Anti-Inflammatory Agents Non-Steroidal Middle Aged Surgery Pethidine Analgesia Epidural Analgesics Opioid Anesthesiology and Pain Medicine medicine.anatomical_structure Anesthesia Injections Intravenous Female business medicine.drug Abdominal surgery |
| Zdroj: | Anaesthesia. 54(1) |
| ISSN: | 0003-2409 |
| Popis: | In this prospective randomised study, pruritus and pain were evaluated in patients undergoing abdominal surgery during which epidural fentanyl was administered. All patients had an epidural catheter inserted at the time of surgery. Epidural fentanyl 100 micrograms was administered intra-operatively and infused at a concentration of 2 micrograms.ml-1 for 48 h postoperatively. All patients received a standard anaesthetic and, in addition, the study group had a 20 mg bolus of tenoxicam intravenously, intra-operatively. Patients receiving tenoxicam demonstrated significantly lower pruritus and pain scores at 30 min, 2, 4, 8 and 24 h postoperatively as well as reduced pethidine requirements for breakthrough pain in the first 24 h. In conclusion, tenoxicam 20 mg significantly reduces the incidence and severity of postoperative pruritus in patients who received peri-operative epidural fentanyl. In addition, it significantly reduces pain and further analgesic requirements postoperatively. |
| Databáze: | OpenAIRE |
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