Redefining gastroesophageal reflux (GER)
| Autor: | Nagammapudur S. Balaji, Dennis Blom, Jeffrey H. Peters, T. R. DeMeester |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
medicine.medical_specialty Sensitivity and Specificity Ph monitoring Gastroenterology Asymptomatic Reference Values Internal medicine Electric Impedance medicine Humans Esophagus False Negative Reactions Esophageal disease business.industry Reflux Gastric Acidity Determination Hydrogen-Ion Concentration medicine.disease Gastrointestinal Contents digestive system diseases medicine.anatomical_structure Gastroesophageal Reflux GERD Esophageal sphincter Non acid reflux Surgery Gases medicine.symptom business |
| Zdroj: | Surgical Endoscopy. 17:1380-1385 |
| ISSN: | 1432-2218 0930-2794 |
| DOI: | 10.1007/s00464-002-8859-x |
| Popis: | Background: The detection of gastroesophageal reflux (GER) has to date been limited to acid exposure observed on 24-h pH monitoring. It is clear, however that nonacid reflux can be a significant clinical problem. Recently, as impedance technology with the capacity to detect all types of reflux (acid, nonacid, liquid, mixed, and air) has been developed. Methods: Seventeen asymptomatic healthy volunteers underwent combined 24-h pH and impedance testing. In all patients, pH was measured at 5 cm above the lower esophageal sphincter (LES), and simultaneous impedance changes were recorded at 3, 5, 7, 9, 15, and 17 cm above the LES. Refluxes were classified as acid (drop in pH 5 sec), Nonacid, short acid, or nonacid delta based on chemical properties; they were further classified as liquid, mixed, or gas based on the physical refluxate detected by impedance changes. The height of the reflux entering the esophagus was classified as distal ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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