Dramatic decline in acute hepatitis B infection and disease incidence rates among adolescents and young people after 12 years of a mass hepatitis B vaccination programme of pre-adolescents in the schools of Catalonia (Spain)
| Autor: | Gloria Carmona, Joan Batalla, E. Navas, Taberner Jl, Luis Salleras, Angela Domínguez, Neus Cardeñosa, M. Bruguera |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Adolescent Serology Seroepidemiologic Studies Epidemiology medicine Humans Hepatitis B Vaccines Child Schools General Veterinary General Immunology and Microbiology business.industry Incidence (epidemiology) Public Health Environmental and Occupational Health Hepatitis B medicine.disease Vaccination Infectious Diseases Immunization Hepatitis b vaccination Spain Immunology Molecular Medicine Female Viral disease business Demography |
| Zdroj: | Vaccine. 23(17-18) |
| ISSN: | 0264-410X |
| Popis: | The aim of the study was to describe the impact of hepatitis B vaccination and disease incidence in adolescents and young people 12 years after the launching of a mass hepatitis B vaccination of pre-adolescents in schools. Vaccination coverage was assessed using administrative and serological data. Infection trends were evaluated by means of seroepidemiological surveys. High levels of vaccination coverage and vaccine-induced immunity were achieved. The resulting low proportions of susceptible adolescents and young people have undoubtedly contributed to the substantial reduction in the prevalence of hepatitis B infection in the 15-24 years age group (0.9 per 100 in 2001 versus 9.3 per 100 in 1986) and in the reported incidence of hepatitis B cases (80% reduction). Over the last 3 years, the declining trend seems to have been halted, although 35% of cases reported during this period corresponded to immigrants. |
| Databáze: | OpenAIRE |
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