Natural ligands of hamster aphrodisin

Autor: Florence Blon, Loïc Briand, Jean-Claude Pernollet, Didier Trotier
Přispěvatelé: Neurobiologie de l'Olfaction et de la Prise Alimentaire (NOPA), Institut National de la Recherche Agronomique (INRA), Centre National de la Recherche Scientifique (CNRS), ProdInra, Migration
Jazyk: angličtina
Rok vydání: 2004
Předmět:
Zdroj: Chemical Senses
Chemical Senses, Oxford University Press (OUP), 2004, 29 (5), pp.425-430
16. Annual Meeting of the European Chemoreception Research Organization (ECRO)
16. Annual Meeting of the European Chemoreception Research Organization (ECRO), Sep 2004, Dijon, France
ISSN: 0379-864X
1464-3553
Popis: The chemical nature of vertebrate pheromones remains largely to be deciphered. Hamster aphrodisin is a rare instance of mammal proteinaceous sexual pheromone. This protein, found in vaginal secretions, facilitates the mounting behaviour of males via activation of a specialized sensory structure named the vomeronasal organ, which activates the accessory olfactory bulb. Since it might carry small pheromonal ligands due to its lipocalin structure, we analysed organic extracts from natural aphrodisin. We identified five predominant compounds specifically bound onto natural aphrodisin as 1-hexadecanol (44.7%), 1-octadecanol (19.5%), Z-9-octadecen-1-ol (18.2%), E-9-octadecen-1-ol (15.4%) and hexadecanoic acid (2.2%). Interestingly, these compounds are also described as part of insect pheromone blends, disclosing the continuing story of amazing coincidences of chemical communication shared by mammals and insects.
Databáze: OpenAIRE