Tear Film Changes Associated with Normal Aging
| Autor: | William D. Mathers, J A Lane, M B Zimmerman |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Adolescent Meibomian gland Normal aging Tear volume Reference Values Ophthalmology medicine Humans Schirmer test Child Aged Chemistry Osmolar Concentration Fluorophotometry Middle Aged Tear osmolarity eye diseases medicine.anatomical_structure Volume (thermodynamics) Tears Reference values Regression Analysis Female sense organs |
| Zdroj: | Cornea. 15:229-234 |
| ISSN: | 0277-3740 |
| DOI: | 10.1097/00003226-199605000-00001 |
| Popis: | We examined a group of normal subjects to evaluate the tear film function by measuring reflex tear capacity using the Schirmer test without anesthetic, steady state tear flow using fluorophotometry, meibomian gland function based on gland drop-out, expressible lipid volume and viscosity, tear loss from evaporation, and tear osmolarity. We found the average tear flow to be 0.19 +/- 0.19 microliters/min, lower than previously measured. The average tear volume was also correspondingly less, 2.74 +/- 2.0 microliters. We found there was a decline associated with advancing age for all parameters except the decay constant and lipid volume. The highest correlations with aging were tear volume (-0.64), Schirmer test (-0.63), and tear osmolarity (0.59). Our results indicate that there is a decline in tear film function throughout life and that tear flow is considerably less than previously estimated. |
| Databáze: | OpenAIRE |
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