Hypothetical Proteins as Predecessors of Long Non-coding RNAs
| Autor: | Vijayaraghava Seshadri Sundararajan, Utkarsh Raj, Tanu Agarwal, Prashanth Suravajhala, Obul Reddy Bandapalli, Girik Malik |
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| Rok vydání: | 2020 |
| Předmět: |
Untranslated region
0303 health sciences 0206 medical engineering Hypothetical proteins aptamers Context (language use) 02 engineering and technology Computational biology Biology Genome Article 03 medical and health sciences Open reading frame lncRNA Intergenic region annotation Genetics transcripts functional genomics Gene Functional genomics 020602 bioinformatics Genetics (clinical) Organism 030304 developmental biology |
| Zdroj: | Current Genomics |
| ISSN: | 1389-2029 |
| Popis: | Hypothetical Proteins [HP] are the transcripts predicted to be expressed in an organism, but no evidence of it exists in gene banks. On the other hand, long non-coding RNAs [lncRNAs] are the transcripts that might be present in the 5’ UTR or intergenic regions of the genes whose lengths are above 200 bases. With the known unknown [KU] regions in the genomes rapidly existing in gene banks, there is a need to understand the role of open reading frames in the context of annotation. In this commentary, we emphasize that HPs could indeed be the predecessors of lncRNAs. |
| Databáze: | OpenAIRE |
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