Giant basal prolactinoma extending into the nasal cavity
| Autor: | Virender K. Khosla, Akira Hakuba, Yuichi Inoue, Misao Nishikawa, Yoshiyasu Iwai, Shuro Nishimura, Junsuke Katsuyama |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Nasal cavity medicine.medical_treatment Anosmia Pituitary adenoma otorhinolaryngologic diseases medicine Humans Pituitary Neoplasms Prolactinoma Nose Craniotomy medicine.diagnostic_test business.industry Magnetic resonance imaging Anatomy medicine.disease Radiography Skull medicine.anatomical_structure Surgery Neurology (clinical) Nasal Cavity medicine.symptom business |
| Zdroj: | Surgical Neurology. 37:280-283 |
| ISSN: | 0090-3019 |
| Popis: | An unusual case of a giant prolactinoma extending to the nasopharynx and nasal cavity is presented. A 35-year-old man admitted for nasal obstruction and visual disturbances was found to have bilateral anosmia, right homonymous hemianopsia, and a right hemiparesis. The serum prolactin level was 13,300 ng/mL. Radiological examination revealed a large mass invading the skull base and extending into the suprasellar region and the left frontal lobe superiorly and into the nasopharynx inferiorly. Subtotal removal was done through a bilateral orbitofrontal craniotomy, which was followed by radiotherapy and bromocriptine administration. Immunohistochemical analysis confirmed a prolactinoma. The rarity of such a tumor, its location and extension, and the usefulness of magnetic resonance imaging and immunohistochemistry are stressed. Pertinent literature is reviewed. |
| Databáze: | OpenAIRE |
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