The Asthma Impairment and Risk Questionnaire (AIRQ) Control Level Predicts Future Risk of Asthma Exacerbations

Autor: David A. Beuther, Kevin R. Murphy, Robert S. Zeiger, Robert A. Wise, William McCann, Joan Reibman, Maureen George, Ileen Gilbert, James M. Eudicone, Hitesh N. Gandhi, Melissa Ross, Karin S. Coyne, Bradley Chipps
Rok vydání: 2022
Předmět:
Zdroj: The Journal of Allergy and Clinical Immunology: In Practice. 10:3204-3212.e2
ISSN: 2213-2198
DOI: 10.1016/j.jaip.2022.08.017
Popis: The Asthma Impairment and Risk Questionnaire (AIRQ) is a 10-item, equally weighted, yes/no control tool validated in patients with asthma aged 12 years and older.To evaluate AIRQ's ability to predict patient-reported exacerbations over 12 months.Patients completed a baseline AIRQ during an in-person enrollment visit and reported exacerbations (ie, asthma-related courses of oral corticosteroids, emergency department/urgent care visits, and hospitalizations) via monthly online surveys. Logistic regressions were performed using AIRQ control level (well-controlled [WC], not well-controlled [NWC], very poorly controlled [VPC]), age, sex, race, and body mass index as covariates and 1 or more and 2 or more exacerbations as the dependent variables (adjusted odds ratios [OR] and 95% Wald CIs). Kaplan-Meier analyses of time to first exacerbation by AIRQ control level were performed.A total of 1,112 patients were enrolled; 1,070 completed 1 or more surveys over 12 months (mean ± SD 10.5 ± 2.8 months); 70.5% female; age 43.9 ± 19.3 years; 20.4% non-White; body mass index 30.6 ± 8.7 kg/mThe AIRQ control level predicts exacerbation risk over 12 months and probability of time to first exacerbation.
Databáze: OpenAIRE