Bevacizumab in treating the cystic components of pediatric low-grade gliomas: A report of four patients
| Autor: | Shehanaz K Ellika, David N. Korones, Erica Levenbaum |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Oncology
Adult Male congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Bevacizumab Adolescent Angiogenesis Inhibitors Brain Edema Astrocytoma Thoracic Vertebrae Ganglioglioma 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Brain Stem Neoplasms Humans Cyst Young adult Central Nervous System Cysts Child Spinal Neoplasms business.industry Brain Neoplasms Hematology Cytoreduction Surgical Procedures Glioma medicine.disease Combined Modality Therapy 030220 oncology & carcinogenesis Child Preschool Pediatrics Perinatology and Child Health Low-Grade Glioma Female Cranial Irradiation business Spinal Cord Compression 030215 immunology medicine.drug |
| Zdroj: | Pediatric bloodcancerREFERENCES. 66(11) |
| ISSN: | 1545-5017 |
| Popis: | Low-grade gliomas (LGG) are among the most common types of brain tumors in children and young adults. These tumors often consist of solid and cystic components. Bevacizumab is a documented treatment for progressive LGG, yet the impact of therapy on the cystic component of these tumors is unknown. We present four patients with prominently cystic LGG treated with bevacizumab at the time of progression. In each case, the cystic component responded to treatment. This is the first known study to investigate bevacizumab's impact on the cystic component of low-grade gliomas. |
| Databáze: | OpenAIRE |
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