Vascular Complications After Liver Transplantation
| Autor: | Ibrahim Astarcioglu, Tarkan Unek, Mucahit Ozbilgin, Tufan Egeli, Eren Kaya, Cihan Agalar, Aycan Gulcu, Sedat Karademir, Engin Barıs Cesmeli |
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| Rok vydání: | 2019 |
| Předmět: |
Transplantation
medicine.medical_specialty business.industry medicine.medical_treatment Incidence (epidemiology) Vascular complication 030230 surgery Liver transplantation Anastomosis Diagnostic tools Surgery 03 medical and health sciences Hepatic artery thrombosis 0302 clinical medicine medicine.anatomical_structure Medicine business Vein Artery |
| Zdroj: | Experimental and Clinical Transplantation. |
| ISSN: | 2146-8427 |
| Popis: | Objectives Vascular complications after liver trans-plant can be lethal. High levels of suspicion and aggressive use of diagnostic tools may help with early diagnosis and treatment. Here, we share our experiences regarding this topic. Materials and methods Adult and pediatric patients who had liver transplant between February 1997 and June 2018 in our clinic were included in the study. Patients were grouped according to age (pediatric patients were those under 18 years old), male versus female, indication for transplant, type of liver transplant, type of vascular complication, treatment, and survival after treatment. We analyzed the statistical incidence of vascular complications according to age, male versus female, and type of liver transplant. Results Our analyses included 607 liver transplant procedures, including 7 retransplants, with 349 (57.4%) from living donors and 258 (42.6%) from deceased donors. Of total patients, 539 were adults (89.8%) and 61 were children (10.2%). Vascular complications occurred in 25 patients (4.1%), with hepatic artery complications seen in 13 patients (2.1%) (10 adults [1.8%] and 3 children [4.9%]), portal vein com-plications seen in 9 patients (1.5%) (6 adults [1.1%] and 3 children [4.9%]), and hepatic vein complications seen in 3 patients (0.5%) (2 adults [0.36%] and 1 child [1.6%]). Rate of vascular complications was statistically higher in pediatric patients (11.4% vs 3.3%; P = .007) and higher but not statistically in recipients of livers from living donors (5.2% vs 2.7%; P = .19). Twelve patients (48.8%) were treated with endovascular approach, and 11 (0.44%) required surgical treatment. Two patients underwent immediate retransplant due to hepatic artery thrombosis. Conclusions Because vascular complications are the most severe complications after liver transplant, there must be close follow-up of vascular anastomoses, particularly early postoperatively, with radiologic methods. In cases of vascular complications, emergent treatment, including endovascular interventions, surgery, and retransplant, must be performed. |
| Databáze: | OpenAIRE |
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