Distinguishing recurrence and new primary tumor as well as the origin of neck metastases in head and neck cancer clinical trials by targeted DNA sequencing

Autor: Torben Steiniche, Magnus Stougaard, J. Lilja-Fischer, Mette Saksø, Jens Overgaard
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Oncology
Male
medicine.medical_specialty
DNA Mutational Analysis
HYPOXIA
DNA sequencing
030218 nuclear medicine & medical imaging
Diagnosis
Differential

03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Recurrent disease
Biomarkers
Tumor

Humans
FAILURE
Radiology
Nuclear Medicine and imaging

Aged
Clinical Trials as Topic
business.industry
Squamous Cell Carcinoma of Head and Neck
Incidence (epidemiology)
Disease progression
Head and neck cancer
Neoplasms
Second Primary

Hematology
General Medicine
Middle Aged
medicine.disease
Head and neck squamous-cell carcinoma
Primary tumor
Clinical trial
PATTERN
Head and Neck Neoplasms
030220 oncology & carcinogenesis
Lymphatic Metastasis
MARKER
Mutation
Disease Progression
Female
SQUAMOUS-CELL CARCINOMA
Neoplasm Recurrence
Local

Tumor Suppressor Protein p53
business
Zdroj: Lilja-Fischer, J K, Saksø, M, Stougaard, M, Steiniche, T & Overgaard, J 2019, ' Distinguishing recurrence and new primary tumor as well as the origin of neck metastases in head and neck cancer clinical trials by targeted DNA sequencing ', Acta Oncologica, vol. 58, no. 10, pp. 1506-1508 . https://doi.org/10.1080/0284186X.2019.1629015
Popis: Patients with head and neck squamous cell carcinoma have a high incidence of recurrences and new primary tumors (NPT) [1,2].Distinguishing between recurrent disease and NPT at the primary tumor sit...
Databáze: OpenAIRE