Chronological changes in epidemiologic features of patients with gallstones over the last 20 years in a single large-volume Korean center
| Autor: | Hongbeom Kim, Youngmin Han, Jiyong Zhao, Yoonhyeong Byun, Jin-Young Jang, Yoo Jin Choi, Wooil Kwon |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Gallstones Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Pigment stone Cholelithiasis Internal medicine Epidemiology medicine Cholesterol business.industry Cholecystolithiasis medicine.disease University hospital Classification chemistry 030220 oncology & carcinogenesis Calcium bilirubinate 030211 gastroenterology & hepatology Surgery Cholecystectomy Original Article Male to female business |
| Zdroj: | Annals of Surgical Treatment and Research |
| ISSN: | 2288-6575 |
| Popis: | Purpose South Korea has a high prevalence of gallstones, the type of which could be influenced by changes in diet and socioeconomic status. Here we aimed to investigate the epidemiological characteristics and changing patterns of gallstones over the past 20 years in Korea. Methods A total of 5,808 patients who underwent cholecystectomy due to gallstones at Seoul National University Hospital between 1996 and 2015 were analyzed. Patients were divided into 4 subgroups: period 1 (1996-2000, n = 792), period 2 (2001-2005, n = 1,215), period 3 (2006-2010, n = 1,525), period 4 (2011-2015, n = 2,276). Gallstones were classified by type: pure cholesterol (PC), mixed cholesterol (MC), calcium bilirubinate (CB), black pigment (BP), and combination (COM). Results The female to male ratio was 1.16 with mean ages of 53.6 and 55.3 years old, respectively. The ratio of cholesterol stones to pigment stones was 0.96:1. The mean age and male to female ratio of the patients increased over time. The proportion of cholesterol vs pigment stone did not differ significantly. Proportions of PC and MC stone subtypes did not change notably, whereas proportion of BP stones increased (34.0% to 45.5%), and CB stones decreased (20.7% to 5.3%). Conclusion Gallstone types and occurrences were affected by environmental changes, and pigment stones remained common in Korea. Although no distinct increase in cholesterol stones was noted, the proportion of CB stones decreased. As the mean age at gallstone presentation increases, BP stones could become more prevalent. |
| Databáze: | OpenAIRE |
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