Evaluation of the coronary flow by the coronary clearance time in patients with cardiac syndrome X

Autor: Murat Celik, Mustafa Koklu, Salim Yaşar, Baris Bugan, Suat Görmel, Mutlu Gungor, Yalçın Gökoğlan, Uygar Cagdas Yuksel, Cem Barçın, Erkan Yildirim
Rok vydání: 2017
Předmět:
Adult
Male
Medicine (General)
medicine.medical_specialty
cardiac syndrome X
Myocardial Infarction
030204 cardiovascular system & hematology
Anterior Descending Coronary Artery
Coronary Angiography
Biochemistry
Clinical Reports
Coronary artery disease
Angina
03 medical and health sciences
R5-920
0302 clinical medicine
Cardiac syndrome X
Internal medicine
medicine.artery
medicine
Humans
030212 general & internal medicine
Myocardial infarction
Aged
Microvascular Angina
Retrospective Studies
business.industry
Microcirculation
Biochemistry (medical)
Thrombosis
Cell Biology
General Medicine
Middle Aged
medicine.disease
Coronary Vessels
microvascular disease
medicine.anatomical_structure
Case-Control Studies
Right coronary artery
cardiovascular system
Cardiology
Female
Coronary clearance frame count
business
Blood Flow Velocity
Artery
Zdroj: Journal of International Medical Research, Vol 46 (2018)
The Journal of International Medical Research
ISSN: 1473-2300
0300-0605
DOI: 10.1177/0300060517743671
Popis: Objective The vessels involved in the microcirculation are too small to be visualized by conventional angiography and no tools are currently available that can directly evaluate the coronary microcirculation. This study evaluated the coronary clearance frame count (CCFC) in patients with cardiac syndrome X (CSX). Methods The retrospective study enrolled patients with angina, who had a positive nuclear imaging test and normal coronary angiography; and a control group consisting of patients who underwent an angiogram to exclude coronary artery disease. Thrombosis in myocardial infarction frame count (TFC) and CCFC for each coronary artery (left anterior descending coronary artery [LAD], circumflex coronary artery [CFX] and right coronary artery [RCA]) were calculated offline. Results A total of 71 patients with CSX and 61 control patients were enrolled in the study. No significant differences were found between the two groups regarding the baseline demographic and clinical variables. The TFC of LAD, CFX and RCA were similar between the two groups. The mean CCFC-LAD, CCFC-CFX and CCFC-RCA were significantly longer in the CSX group compared with the control group. Conclusion CCFC is a simple, quantitative and highly reproducible method that might be used as a marker of coronary microvascular dysfunction.
Databáze: OpenAIRE
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