Depression relapse prophylaxis with Mindfulness-Based Cognitive Therapy: replication and extension in the Swiss health care system

Autor: Jean-Michel Aubry, Lucio Bizzini, Gilles Bertschy, Zindel V. Segal, Guido Bondolfi, Béatrice Weber Rouget, Martial Van der Linden, Marianne Gex-Fabry, Françoise Jermann, Christiane Gonzalez, Lusmila Myers-Arrazola
Rok vydání: 2009
Předmět:
Adult
Male
Research Report
medicine.medical_specialty
Mindfulness
Remission
medicine.medical_treatment
law.invention
03 medical and health sciences
Therapeutic approach
0302 clinical medicine
Randomized controlled trial
Mindfulness practice
law
Internal medicine
medicine
Secondary Prevention
Humans
Prospective Studies
Prospective cohort study
Psychiatry
Depression (differential diagnoses)
Mindfulness-based cognitive therapy
Aged
Aged
80 and over
Psychiatric Status Rating Scales
Depressive Disorder
Cognitive Behavioral Therapy
Cognition
Middle Aged
Combined Modality Therapy
Depressive relapse prophylaxis
030227 psychiatry
3. Good health
Psychiatry and Mental health
Clinical Psychology
Meditation
Treatment Outcome
Cognitive therapy
Psychotherapy
Group
Female
MBCT
Psychology
Delivery of Health Care
030217 neurology & neurosurgery
Switzerland
Follow-Up Studies
Zdroj: Journal of Affective Disorders
ISSN: 1573-2517
Popis: Background Mindfulness-Based Cognitive Therapy (MBCT) is a group intervention that integrates elements of Cognitive Behavioural Therapy (CBT) with components of mindfulness training to prevent depressive relapse. The efficacy of MBCT compared to Treatment As Usual (TAU), shown in two randomized controlled trials indicates a significant decrease in 1-year relapse rates for patients with at least three past depressive episodes. The present study is the first independent replication trial comparing MBCT + TAU to TAU alone across both language and culture (Swiss health care system). Methods Sixty unmedicated patients in remission from recurrent depression (≥ 3 episodes) were randomly assigned to MBCT + TAU or TAU. Relapse rate and time to relapse were measured over a 60 week observation period. The frequency of mindfulness practices during the study was also evaluated. Results Over a 14-month prospective follow-up period, time to relapse was significantly longer with MBCT + TAU than TAU alone (median 204 and 69 days, respectively), although both groups relapsed at similar rates. Analyses of homework adherence revealed that following treatment termination, the frequency of brief and informal mindfulness practice remained unchanged over 14 months, whereas the use of longer formal meditation decreased over time. Limitations Relapse monitoring was 14 months in duration and prospective reporting of mindfulness practice would have yielded more precise frequency estimates compared to the retrospective methods we utilized. Conclusions Further studies are required to determine which patient characteristics, beyond the number of past depressive episodes, may predict differential benefits from this therapeutic approach.
Databáze: OpenAIRE
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