An assessment of perfusion deficits in decompression illness using 99Tcm HMPAO SPET and statistical parametric mapping
| Autor: | Howard G. Gemmell, J. C. Dickson, Roger T. Staff, F. I. McKiddie |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Diving Hemodynamics chemistry.chemical_element Technetium Statistical parametric mapping Decompression sickness Technetium Tc 99m Exametazime Reference Values Image Processing Computer-Assisted medicine Embolism Air Humans Radiology Nuclear Medicine and imaging Tomography Emission-Computed Single-Photon business.industry Brain Decompression illness General Medicine Middle Aged Decompression Sickness medicine.disease Intracranial Embolism chemistry Cerebral blood flow Cerebrovascular Circulation Data Interpretation Statistical Radiopharmaceuticals business Nuclear medicine Perfusion |
| Zdroj: | Nuclear Medicine Communications. 22:423-428 |
| ISSN: | 0143-3636 |
| DOI: | 10.1097/00006231-200104000-00011 |
| Popis: | Aim The aim of this study was to use statistical parametric mapping (SPM) to investigate differences in the regional cerebral blood flow (rCBF) of decompression illness (DCI) and non-diving control subjects. Methods Twenty DCI subjects were imaged using 99Tcm hexamethylproplylene amine oxime (HMPAO) single photon emission tomography (SPET) within days of their incident of DCI, and on a second occasion between 2 and 27 months after their DCI event. SPM was used to make a comparison between decompression illness studies and a second group of non-diving control studies for both early and late imaging of DCI. A paired comparison of early and late imaging was also performed testing for correlation between time of imaging and changes in the rCBF pattern. Results The comparison between control subjects and early imaging of decompression illness showed a large, significant (P=0.002), irregularly shaped, multi-focal area of reduced uptake in the left occipitoparieto-temporal region of the brain. Comparisons between control and repeat decompression illness imaging studies showed two areas of reduced uptake. The first was similar to that found in the initial comparison although it was less significant (P=0.035). The second region was similar but contra-lateral to the first region with significance P |
| Databáze: | OpenAIRE |
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