Cardiovascular effects of neuromuscular blockade during induced hypothermia
| Autor: | Richard K. H. Wyse, E. D. Silove, Margaret L. Godley, Kenneth C. Welham |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Physiology
medicine.drug_class Hemodynamics Contractility Electrocardiography Hypothermia Induced Physiology (medical) Heart rate Medicine Animals Cardiac Output Pharmacology Neuromuscular Blockade Sheep Gallamine Triethiodide business.industry Mean Aortic Pressure Muscle relaxant Stroke Volume Hypothermia Preload Anesthesia Vascular Resistance medicine.symptom Neuromuscular Blocking Agents business |
| Zdroj: | Clinical and experimental pharmacologyphysiology. 11(2) |
| ISSN: | 0305-1870 |
| Popis: | SUMMARY 1. Young lambs were used to study the effects of progressive cooling and rewarming on cardiovascular function during neuromuscular blockade induced by gallamine. 2. Initially, it was shown that gallamine exerted no immediate, direct haemodynamic effect in normothermic or hypothermic lambs (cooled by 10°C). 3. By comparison with hypothermic controls, neuromuscular blockade was associated with increases in left ventricular (LV) max dP/dt (153%; P |
| Databáze: | OpenAIRE |
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