Biorefinery of Rice Husk to Obtain Functionalized Bioactive Compounds

Autor: Mary Lopretti, H. Cerecetto, N. Lecot, Felipe Orozco, L. Bola駉s, José Vega-Baudrit, Gabriela Lluberas, G. Montes De Oca, AR Rodriguez
Přispěvatelé: Lopretti Mary Isabel, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares., Lecot Calandria Nicole Valerie, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares., Rodríguez A., Universidad de la República (Uruguay). Facultad de Química., Lluberas Nuñez Maria Gabriela, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares., Orozco F., Bolaños L., Montes de Oca G., Cerecetto Hugo, Universidad de la República (Uruguay). Facultad de Ciencias. Centro de Investigaciones Nucleares., Vega Baudrit José Roberto
Rok vydání: 2019
Předmět:
Zdroj: COLIBRI
Universidad de la República
instacron:Universidad de la República
ISSN: 2164-6341
DOI: 10.32604/jrm.2019.00008
Popis: The biomass industrialization valorisation of grains and cereals is considered an opportunity for the countries where agro-industrial activity is one of its main economic activities, rendering new higher-value products with a concomitant solution to waste accumulation issues. To that end, in this work we describe and characterise bioactive compounds generation from rice husk by semisolid fermentation, obtained from 500 g of the material at room temperature and 60% humidity with mixed cultures of Phanerochaete chrysosporium and Gloeophyllum trabeum. The extract was evaluated in different situations: murine mammary tumour cells (4T1), normal cells (NIH 3T3) and in Lactobacillus acidophilus, and Trichoderma harzianum. The results exhibited that the extract inhibited 4T1 cells at concentrations higher than 20μg/mL, but did not inhibit normal cells, and displayed germicide activity after 3 days incubations. We propose that these functionalized compounds have a potential application in industry/agriculture/medicine obtained from rice husk waste.
Databáze: OpenAIRE
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