Study on EEG power and coherence in patients with mild cognitive impairment during working memory task
| Autor: | Zheng-yan Jiang |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Statistics as Topic Electroencephalography Audiology Severity of Illness Index General Biochemistry Genetics and Molecular Biology Task Performance and Analysis medicine Humans Coherence (signal processing) In patient Diagnosis Computer-Assisted General Pharmacology Toxicology and Pharmaceutics Mild cognitive impairment (MCI) Cognitive impairment Aged General Veterinary medicine.diagnostic_test business.industry Working memory Brain General Medicine Middle Aged medicine.disease Biomedicine Task (computing) Memory Short-Term Correlation analysis Female Cognition Disorders business |
| Zdroj: | Journal of Zhejiang University SCIENCE B. 6:1213-1219 |
| ISSN: | 1862-1783 1673-1581 |
| DOI: | 10.1631/jzus.2005.b1213 |
| Popis: | To investigate the features of electroencephalography (EEG) power and coherence at rest and during a working memory task of patients with mild cognitive impairment (MCI). Thirty-five patients (17 males, 18 females; 52:_71 years old) and 34 sex-and age-matched controls (17 males, 17 females; 51:_63 years old) were recruited in the present study. Mini-Mental State Examination (MMSE) of 35 patients with MCI and 34 normal controls revealed that the scores of MCI patients did not differ significantly from those of normal controls (P>0.05). Then, EEGs at rest and during working memory task with three levels of working memory load were recorded. The EEG power was computed over 10 channels: right and left frontal (F3, F4), central (C3, C4), parietal (P3, P4), temporal (T5, T6) and occipital (O1, O2); inter-hemispheric coherences were computed from five electrode pairs of F3-F4, C3-C4, P3-P4, T5-T6 and O1-O2 for delta (1.0:_3.5 Hz), theta (4.0:_7.5 Hz), alpha-1 (8.0:_10.0 Hz), alpha-2 (10.5:_13.0 Hz), beta-1 (13.5:_18.0 Hz) and beta-2 (18.5:_30.0 Hz) frequency bands. All values of the EEG power of MCI patients were found to be higher than those of normal controls at rest and during working memory tasks. Furthermore, the values of EEG power in the theta, alpha-1, alpha-2 and beta-1 bands of patients with MCI were significantly high (P |
| Databáze: | OpenAIRE |
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