Morning blood pressure surge is associated with autonomic neuropathy and peripheral vascular disease in patients with diabetes
| Autor: | Roberto Morganti, Cinzia D’Amato, Vincenza Spallone, Carla Greco, Federica Di Gennaro, Davide Lauro, Susanna Longo, Diana Corradini |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Diabetic neuropathy Ambulatory blood pressure Population Diastole Blood Pressure 030204 cardiovascular system & hematology Autonomic Nervous System Settore MED/13 - Endocrinologia 03 medical and health sciences 0302 clinical medicine Diabetic Neuropathies Internal medicine Diabetes mellitus Diabetes Mellitus Internal Medicine medicine Humans 030212 general & internal medicine education Aged Peripheral Vascular Diseases education.field_of_study Vascular disease business.industry Blood Pressure Monitoring Ambulatory Middle Aged medicine.disease Circadian Rhythm Cross-Sectional Studies Blood pressure Hypertension Cardiology Metabolic syndrome business |
| Popis: | Although vascular and autonomic nervous system have been involved in the regulation of morning surge in blood pressure (MBPS), data on clinical correlates of MBPS in diabetic population are scarce, in particular with regard to diabetic complications. This study was aimed at investigating predictors and correlates of MBPS in diabetes. In a cross-sectional study including 167 patients with diabetes (age 58.5 ± 11.1 years, duration 15.9 ± 12.1 years), clinical variables, diabetic and neuropathic complications, and MBPS (using 24-h ambulatory blood pressure monitoring) were measured. The upper quartile of MBPS (>30.5 mmHg) was associated with higher values of waist circumference (P = 0.027), triglycerides (P = 0.021), and Michigan Diabetic Neuropathy Score (P = 0.042), with lower HDL cholesterol (P = 0.030), and with the presence of cardiovascular autonomic neuropathy (CAN) (P = 0.016) and peripheral vascular disease (PVD) (P 10%) (P = 0.012), and MBPS was positively related to systolic (rho = 0.41, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|