A Multicenter Retrospective Case Study of Anaphylaxis Triggers by Age in Korean Children
| Autor: | Gwang Cheon Jang, You Hoon Jeon, Kyung Won Kim, Yong Mean Park, Hyeon Jong Yang, Ji Won Kwon, Kyu-Earn Kim, Jinho Yu, Myung Hyun Sohn, Hyung Young Kim, Dong In Suh, So-Yeon Lee, Jihyun Kim, Soo Young Lee, Kangmo Ahn, Young Min Ahn, Woo Kyung Kim, Jung Hyun Kwon, Bok Yang Pyun, Taek Ki Min, Yong Ju Lee, Hae Ran Lee, Soo-Jong Hong, Tae Won Song, Hye Yung Yum, Hye Young Kim, Jin Tack Kim, Hyun Hee Kim, Sung-Won Kim, Jeong Hee Kim |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pulmonary and Respiratory Medicine
Pediatrics medicine.medical_specialty medicine.drug_class Immunology Antibiotics Milk allergy 03 medical and health sciences 0302 clinical medicine Age groups children Epidemiology medicine Immunology and Allergy 030212 general & internal medicine Anaphylaxis Radiocontrast Media business.industry Medical record Retrospective cohort study medicine.disease 030228 respiratory system Original Article epidemiology business |
| Zdroj: | Allergy, Asthma & Immunology Research |
| ISSN: | 2092-7363 2092-7355 |
| Popis: | PURPOSE Although anaphylaxis is recognized as an important, life-threatening condition, data are limited regarding its triggers in different age groups. We aimed to identify anaphylaxis triggers by age in Korean children. METHODS We performed a retrospective review of medical records for children diagnosed with anaphylaxis between 2009 and 2013 in 23 secondary or tertiary hospitals in South Korea. RESULTS A total of 991 cases (mean age=5.89±5.24) were reported, with 63.9% involving patients younger than 6 years of age and 66% involving male children. Food was the most common anaphylaxis trigger (74.7%), followed by drugs and radiocontrast media (10.7%), idiopathic factors (9.2%), and exercise (3.6%). The most common food allergen was milk (28.4%), followed by egg white (13.6%), walnut (8.0%), wheat (7.2%), buckwheat (6.5%), and peanut (6.2%). Milk and seafood were the most common anaphylaxis triggers in young and older children, respectively. Drug-triggered anaphylaxis was observed more frequently with increasing age, with antibiotics (34.9%) and nonsteroidal anti-inflammatory drugs (17.9%) being the most common causes. CONCLUSIONS The most common anaphylaxis trigger in Korean children was food. Data on these triggers show that their relative frequency may vary by age. |
| Databáze: | OpenAIRE |
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