Neurosyphilis presenting with psychotic symptoms and status epilepticus

Autor: Bingdi Xie, Yuanrong Yao, Enqiang Huang, Yan Cheng
Rok vydání: 2011
Předmět:
Zdroj: Neurological Sciences. 33:99-102
ISSN: 1590-3478
1590-1874
DOI: 10.1007/s10072-011-0563-y
Popis: The widespread use of antibiotics in recent years has considerably modified the clinical features of neurosyphilis. Presently, atypical or masked forms of this disease often occur and obscure diagnosis, despite a thorough history and clinical work-up. Here, we report a patient with neurosyphilis presenting with psychotic symptoms who then developed status epilepticus and left limb weakness. Diffusion-weighted magnetic resonance imaging showed hyperintensity involving the right parietal, occipital and temporal lobes and the thalamus. Subsequent serological and cerebrospinal fluid tests confirmed the diagnosis of neurosyphilis. The coexistence of meningovascular syphilis, syphilitic meningitis, and general paresis resulted in the complex manifestation of this patients' condition, as described here in terms of the unusual presentation, evolution, and final diagnosis.
Databáze: OpenAIRE