The map-1 gene family in root-knot nematodes, Meloidogyne spp.: a set of taxonomically restricted genes specific to clonal species
| Autor: | Philippe Castagnone-Sereno, Karine Mulet, Cathy Iachia, Iva Tomalova |
|---|---|
| Přispěvatelé: | Institut Sophia Agrobiotech (ISA), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Recherche Agronomique (INRA), Centre National de la Recherche Scientifique (CNRS), INRA (Institut National de la Recherche Agronomique), EU grant from the ERASMUS Mobility Programme |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Evolutionary Genetics
0106 biological sciences Animal Evolution Sequence analysis [SDV]Life Sciences [q-bio] Molecular Sequence Data lcsh:Medicine Biology 01 natural sciences Genome Molecular Genetics 03 medical and health sciences Eukaryotic Evolution Model Organisms Phylogenetics Gene duplication Genetics Meloidogyne incognita Animals Gene family Evolutionary Systematics Amino Acid Sequence Tylenchoidea lcsh:Science Gene Phylogeny Animal Management 030304 developmental biology Evolutionary Biology 0303 health sciences Multidisciplinary Sequence Homology Amino Acid Phylogenetic tree lcsh:R Computational Biology Agriculture Animal Models biology.organism_classification Organismal Evolution Multigene Family [SDE]Environmental Sciences lcsh:Q Animal Genetics Research Article 010606 plant biology & botany |
| Zdroj: | PLoS ONE PLoS ONE, Public Library of Science, 2012, 7 (6), ⟨10.1371/journal.pone.0038656⟩ Plos One 6 (7), . (2012) PLoS ONE, Vol 7, Iss 6, p e38656 (2012) |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0038656⟩ |
| Popis: | International audience; Taxonomically restricted genes (TRGs), i.e., genes that are restricted to a limited subset of phylogenetically related organisms, may be important in adaptation. In parasitic organisms, TRG-encoded proteins are possible determinants of the specificity of host-parasite interactions. In the root-knot nematode (RKN) Meloidogyne incognita, the map-1 gene family encodes expansin-like proteins that are secreted into plant tissues during parasitism, thought to act as effectors to promote successful root infection. MAP-1 proteins exhibit a modular architecture, with variable number and arrangement of 58 and 13-aa domains in their central part. Here, we address the evolutionary origins of this gene family using a combination of bioinformatics and molecular biology approaches. Map-1 genes were solely identified in one single member of the phylum Nematoda, i.e., the genus Meloidogyne, and not detected in any other nematode, thus indicating that the map-1 gene family is indeed a TRG family. A phylogenetic analysis of the distribution of map-1 genes in RKNs further showed that these genes are specifically present in species that reproduce by mitotic parthenogenesis, with the exception of M. floridensis, and could not be detected in RKNs reproducing by either meiotic parthenogenesis or amphimixis. These results highlight the divergence between mitotic and meiotic RKN species as a critical transition in the evolutionary history of these parasites. Analysis of the sequence conservation and organization of repeated domains in map-1 genes suggests that gene duplication(s) together with domain loss/duplication have contributed to the evolution of the map-1 family, and that some strong selection mechanism may be acting upon these genes to maintain their functional role(s) in the specificity of the plant-RKN interactions. |
| Databáze: | OpenAIRE |
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