Long-term incidence of urinary tract infection after ureteral reimplantation for primary vesicoureteral reflux
| Autor: | Katherine C. Hubert, Caleb P. Nelson, Alan B. Retik, Ilina Rosoklija, Michaella M. Prasad, Paul Kokorowski, Lin Huang |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Urology Urinary system Population urologic and male genital diseases Vesicoureteral reflux Disease-Free Survival Postoperative Complications medicine Humans Child education Proportional Hazards Models Retrospective Studies Vesico-Ureteral Reflux Multivariate survival analysis education.field_of_study Pyelonephritis business.industry Proportional hazards model Incidence Incidence (epidemiology) medicine.disease female genital diseases and pregnancy complications Renal scarring Child Preschool Replantation Multivariate Analysis Urinary Tract Infections Pediatrics Perinatology and Child Health Female Ureter business Ureteral reimplantation |
| Zdroj: | Journal of Pediatric Urology. 9:92-98 |
| ISSN: | 1477-5131 |
| Popis: | Objective To determine the incidence of urinary tract infection (UTI) after ureteral reimplantation (UR) for primary vesicoureteral reflux (VUR). Materials and methods In this retrospective review, the pyelonephritis-free survival of patients with primary VUR who underwent open UR from January 1990 to December 2002 was assessed using a Cox proportional hazards analysis. Results 1076 patients underwent open UR for primary VUR. 73.0% were female; median age was 4.7 years. 80.1% presented with UTI. Clinical success rate for non-tapered UR was 96.5%. Median follow-up was 2.9 years. 21.8% had at least one postoperative UTI. 6.5% had postoperative pyelonephritis (POP) at a median of 21 months postoperatively. On multivariate survival analysis female gender (OR 9.97, 95% CI 3.07–32.34), preoperative VUR grade ≥3 (2.14, 1.25–3.69), breakthrough preoperative UTI (2.00, 1.22–3.25), and preoperative renal scarring (1.86, 1.15–2.99) were associated with POP. Conclusion POP is rare on long-term follow-up, suggesting that UR is effective in reducing pyelonephritis in this population. |
| Databáze: | OpenAIRE |
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