The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review
| Autor: | Rachid Aboutaieb, Issam Jandou, Adil Debbagh, Amine Moataz, Mohammed Hicham Mouqtassid, Mohammed Dakir |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases medicine.medical_treatment Urinary system Case Report Normetanephrine Malignancy Palpation Cystectomy Pheochromocytoma 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Methoxylated derivative Medicine Bladder pheochromocytoma neoplasms Metanephrine Ectopic pheochromocytoma medicine.diagnostic_test business.industry Benignity medicine.disease nervous system chemistry Partial cystectomy 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery Radiology business hormones hormone substitutes and hormone antagonists |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| DOI: | 10.1016/j.ijscr.2020.11.132 |
| Popis: | Highlights • Pheochromocytoma is a tumor developed at the expense of chromaffin tissues. • Extra-adrenal localization of pheochromocytoma is rare. • The main problem with these tumors is to affirm their benignity or malignancy. • Ectopic pheochromocytomas have a malignant development once in two. • Ectopic pheochromocytoma presents a diagnostic and therapeutic dilemma. Introduction Extra-adrenal localization of pheochromocytoma is rare. Its clinical revelation is paroxysmal but maybe in the form of permanent hypertension resistant to treatment. The main problem with these tumors is to affirm their benignity or malignancy, ectopic pheochromocytomas have a malignant development once in two. Case presentation We report the observation of a 39-year-old woman hypertensive on Amlodipine. She presents for sweating, headache, and palpation. The dosage of urinary metabolites revealed a marked increase in metanephrine and normetanephrine. Imagery had shown, at the expense of the left lateral wall of the bladder, a budding tissue formation with irregular contours which was significantly enhanced after injection of PDC. The diagnosis of an ectopic pheochromocytoma was accepted. The patient underwent a partial cystectomy, the postoperative consequences of which were unremarkable. Discussion Threatening secretory syndromes are rare medical situations that require urgent management. Pheochromocytoma can be seen at any age from childhood to old age. The treatment of pheochromocytoma is surgical, once the stages of positive and topographic diagnosis have been carried out, the patient must be immediately entrusted to a team of trained surgeons and anesthetists. The prognosis remains unpredictable, hence the interest in prolonged monitoring. Conclusion Pheochromocytoma is a tumor developed at the expense of chromaffin tissues, extra-adrenal localizations exist, but remain rare. It is a pathology that presents a diagnostic and therapeutic dilemma in which patients require regular and prolonged postoperative monitoring to detect a possible metastasis or recurrence. |
| Databáze: | OpenAIRE |
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