Effects of a lifestyle education program on glycemic control among patients with diabetes at Kigali University Hospital, Rwanda: A randomized controlled trial
| Autor: | Donatille Mukantagwabira, Joseph Uwiragiye, Etienne Amendezo, Jeanne Bisimwa, Patrick Kavabushi, Henriette Umulisa, Bernard Ndayambaje, B. H. Robinson, Vincent Karamuka, Scholastique Niyomwungeri, Vincent Dusabejambo, Cyprien Ntirenganya, Charlotte Bavuma, Henriette Uwintwali Marie, David Walker Timothy |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Blood Glucose Counseling Male medicine.medical_specialty Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism law.invention Hospitals University 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Patient Education as Topic Randomized controlled trial law Intervention (counseling) Diabetes mellitus Internal Medicine medicine Humans Healthy Lifestyle 030212 general & internal medicine Aged Glycemic Glycated Hemoglobin Adult patients business.industry Rwanda General Medicine Middle Aged medicine.disease University hospital Test (assessment) Diabetes Mellitus Type 2 chemistry Physical therapy Female Glycated hemoglobin business |
| Zdroj: | Diabetes Research and Clinical Practice. 126:129-137 |
| ISSN: | 0168-8227 |
| Popis: | Evidence to show whether lifestyle intervention programs are beneficial for patients with diabetes in resource-limited countries is lacking. The present study assessed the additional efficacy of a structured lifestyle education program, as compared to the current standard of diabetic care in Rwanda.251 consecutive adult patients attending a tertiary diabetic care practice were randomly assigned to either an intervention group (standard of care plus monthly lifestyle group education sessions of 45min duration) or to a control group. The primary outcome was between-groups difference in glycated hemoglobin (HbA1c) observed after 12-months follow up. Outcome measures in the intervention and control groups were compared using the ANCOVA test with a two-sided significance of 5%.Of the 251 subjects recruited, 223 were included in the analysis; of whom 115 were assigned to the intervention group, and 108 to the control group. After 12-months, the median HbA1c levels reduced by 1.70 (95% CI: -2.09 to -1.31; p0.001) in the intervention group; and by 0.52 (95% CI: -0.95 to -0.10; p=0.01) in the control group. The difference in HbA1c reduction between the intervention and control groups was statistically significant (p0.001) after adjustment for subjects' age, sex, education level, BMI, diabetes duration and diabetic medications.This study demonstrated that a structured lifestyle group education program for people with diabetes is an attractive option in a resource-limited setting, as it showed significant benefits in improved glycemic control over a 12-month period.ClinicalTrials.gov: NCT02032108. |
| Databáze: | OpenAIRE |
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