Preserved right ventricular function but increased right atrial contractile demand in altitude-induced pulmonary hypertension
| Autor: | Bernhard Reich, Peter Schmidt, Sebastian Fried, Marc M. Berger, Mahdi Sareban, Josef Niebauer, Franziska Macholz, Heimo Mairbäurl, Tabea Perz |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Contraction (grammar) Acclimatization Hypertension Pulmonary Atrial Function Right Right atrial Pulmonary hypertension Afterload Internal medicine medicine.artery medicine Humans Radiology Nuclear Medicine and imaging Low altitude Original Paper Ventricular function business.industry Altitude Atrial function Middle Aged Effects of high altitude on humans medicine.disease Myocardial Contraction Echocardiography Doppler Echocardiography Pulmonary artery Ventricular Function Right Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | The International Journal of Cardiovascular Imaging |
| ISSN: | 1573-0743 1569-5794 |
| Popis: | Purpose Ascent to high altitude increases right ventricular (RV) afterload and decreases myocardial energy supply. This study evaluates physiologic variables and comprehensive echocardiographic indices of RV and right atrial (RA) function following rapid ascent to high altitude. Methods Fifty healthy volunteers actively ascended from 1130 to 4559 m in Results sPAP increased from baseline (24 ± 4 mmHg) to the first altitude examination (39 ± 8 mmHg, p p = 0.07) secondary to a significant increase of RA contraction strain (19.2 ± 6.4 vs. 25.4 ± 9.6%, p Conclusion Active and rapid ascent of healthy individuals to 4559 m is associated with an increased contractile performance of the RA that compensates for the increased workload of the RV. |
| Databáze: | OpenAIRE |
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