Consecutive appearance of corneal subepithelial infiltrates after intravitreous bevacizumab injections
| Autor: | Nirit Bourla, Assaf Dotan, Dan Bourla, Dov Weinberger, Israel Kremer |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Vascular Endothelial Growth Factor A
medicine.medical_specialty genetic structures Bevacizumab medicine.medical_treatment Physical examination Angiogenesis Inhibitors Antibodies Monoclonal Humanized Corneal Diseases Injections Macular Degeneration Recurrence Ophthalmology medicine Humans Glucocorticoids Aged medicine.diagnostic_test business.industry Granuloma Foreign-Body Epithelium Corneal Antibodies Monoclonal Macular degeneration medicine.disease eye diseases Epidemic Keratoconjunctivitis Vitreous Body Retreatment Female sense organs business medicine.drug Topical steroid |
| Zdroj: | Cornea. 29(6) |
| ISSN: | 1536-4798 |
| Popis: | PURPOSE To report a case of corneal subepithelial infiltrates appearing after intravitreous bevacizumab injections. METHODS A review of the patient's history and clinical examination findings in a patient who had epidemic keratoconjunctivitis more then 20 years before treatment with bevacizumab for age-related macular degeneration. RESULTS After the third and fourth bevacizumab injections, the patient presented with unilateral corneal subepithelial infiltrates. The infiltrates were accompanied by mild anterior chamber reaction and resolved with topical steroid treatment. CONCLUSIONS Treatment with intravitreous bevacizumab may precipitate an immune response leading to the appearance of corneal subepithelial infiltrates. |
| Databáze: | OpenAIRE |
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