Clinicopathological characteristics and long-term prognosis of screening detected non-palpable breast cancer by ultrasound in hospital-based Chinese population (2001-2014)
| Autor: | Feng Cai, R Yao, Jing Zhang, Yan Lin, Songjie Shen, Qian-Qian Xu, Bo Pan, Qingli Zhu, Jie Shi, Changjun Wang, Qiang Sun, Feng Mao, Jinghong Guan, Yuxin Jiang, Zhiyong Liang, Shan-Shan You, Yidong Zhou |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
China medicine.medical_specialty Breast surgery medicine.medical_treatment Breast Neoplasms Sensitivity and Specificity Asymptomatic 030218 nuclear medicine & medical imaging 03 medical and health sciences Breast cancer screening 0302 clinical medicine Breast cancer non-palpable breast cancer medicine Humans Mass Screening Mammography Early Detection of Cancer Neoplasm Staging Gynecology Chinese population medicine.diagnostic_test ultrasound business.industry screening General surgery Hospital based Middle Aged Prognosis medicine.disease Survival Analysis Oncology 030220 oncology & carcinogenesis Female Ultrasonography Mammary Neoplasm Grading medicine.symptom business Research Paper |
| Zdroj: | Oncotarget |
| ISSN: | 1949-2553 |
| DOI: | 10.18632/oncotarget.12319 |
| Popis: | // Bo Pan 1, * , Ru Yao 1, * , Qing-Li Zhu 2, * , Chang-Jun Wang 1 , Shan-Shan You 2 , Jing Zhang 2 , Qian-Qian Xu 1 , Feng Cai 3 , Jie Shi 4 , Yi-Dong Zhou 1 , Feng Mao 1 , Yan Lin 1 , Jing-Hong Guan 1 , Song-Jie Shen 1 , Zhi-Yong Liang 4 , Yu-Xin Jiang 2 , Qiang Sun 1 1 Department of Breast Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P. R. China (100730) 2 Department of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P. R. China (100730) 3 Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P. R. China (100730) 4 Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P. R. China (100730) * These authors have contributed equally to this work Correspondence to: Qiang Sun, email: sunqiang_pumc@163.com Keywords: non-palpable breast cancer, screening, ultrasound, prognosis Received: August 01, 2016 Accepted: September 12, 2016 Published: September 28, 2016 ABSTRACT Purpose: The mainstay modality of breast cancer screening in China is the hospital-based opportunistic screening among asymptomatic self-referred women. There is little data about the ultrasound (US) detected non-palpable breast cancer (NPBC) in Chinese population. Methods: We analyzed 699 consecutive NPBC from 1.8-2.3 million asymptomatic women from 2001 to 2014, including 572 US-detected NPBC from 3,786 US-positive women and 127 mammography (MG) detected NPBC from 788 MG-positive women. The clinicopathological features, disease-free survival (DFS) and overall survival (OS) were compared between the US- and MG-detected NPBC. Prognostic factors of NPBC were identified. Results: Compared to MG, US could detect more invasive NPBC (83.6% vs 54.3%, p 14%, 46.3% vs 37.0%, p=0.031) cancers and more NPBC who received chemotherapy (40.7% vs 21.3%, p |
| Databáze: | OpenAIRE |
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