Accuracy and precision of perfusion lung scintigraphy versus 133Xe-radiospirometry for preoperative pulmonary functional assessment of patients with lung cancer
| Autor: | Michel Rossi, Denis Mariano-Goulart, Frédéric Comte, E. Barbotte, Célia Basurko |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Lung Neoplasms Pulmonary insufficiency Scintigraphy Carcinoma Non-Small-Cell Lung Forced Expiratory Volume medicine Humans Radiology Nuclear Medicine and imaging Respiratory system Stage (cooking) Radionuclide Imaging Lung cancer Aged Neoplasm Staging Aged 80 and over Lung medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Respiratory Function Tests medicine.anatomical_structure Spirometry Orthopedic surgery Female Radiology business Perfusion Xenon Radioisotopes |
| Zdroj: | European Journal of Nuclear Medicine and Molecular Imaging. 33:1048-1054 |
| ISSN: | 1619-7089 1619-7070 |
| DOI: | 10.1007/s00259-006-0087-5 |
| Popis: | Purpose: This study sought to determine whether 133Xe-radiospirometry (XRS) successfully selects patients able to undergo lung resection without postoperative respiratory complications and whether perfusion lung scintigraphy (PLS) is likely to provide a similar selection of patients for certain tumour stages. Methods: Two hundred and eighty-four patients with resectable lung cancer underwent preoperative assessment of postoperative forced expiratory volume in 1 s (FEV1) by XRS and PLS. Correlations, Bland and Altman analysis and contingency tables were used to analyse the difference between the two predictive techniques. Results: One hundred and sixty patients underwent lung resection on the basis of XRS preoperative testing only. None of them developed respiratory insufficiency. Despite a close correlation, the limits of agreement between predicted FEV1 by XRS and PLS exceeded ±0.3 l/s. For tumour stages T1Nx and T2N0, PLS underestimated postoperative FEV1 whereas it overestimated this parameter for stage III. Conclusion: XRS accurately selects patients able to undergo lung resection without postoperative pulmonary insufficiency. The agreement between XRS and PLS is unacceptable. When only PLS is available, higher thresholds for patients with stage III cancers and lower thresholds for those with stage I cancers should be used to decide on operability. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|