Material properties of porcine parietal cortex
| Autor: | Brittany Coats, Susan S. Margulies |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Swine
Traumatic brain injury Homogeneity (statistics) Models Neurological Rehabilitation Thalamus Biomedical Engineering Biophysics Posterior parietal cortex Anatomy Biology Corpus callosum medicine.disease White matter medicine.anatomical_structure Corona radiata Cerebral cortex Parietal Lobe Models Animal medicine Animals Humans Computer Simulation Orthopedics and Sports Medicine |
| Zdroj: | Journal of Biomechanics. 39:2521-2525 |
| ISSN: | 0021-9290 |
| Popis: | Computational models of the head can be used to simulate events associated with traumatic brain injury and to design protective equipment and environments. Accurate material property descriptions of biological tissues are crucial to the development of computational models that mimic human responses. Recent finite element models of adult head injury assign distinct homogeneous properties to white and gray matter regions within the brain, based on limited regional data. However, white matter is usually considered homogeneous, despite recent reports of significant mechanical property differences between corpus callosum and corona radiata. In this study, we extend our investigation of homogeneity to gray matter by measuring stiffness of cerebral cortex and comparing it to thalamus from our previous work. Using a parallel plate shear-testing device, we performed a sequence of stress relaxation tests at 2.5%, 5%, 10%, 20%, 30%, 40%, and then 50% strain. Force and displacement were measured and used to determine the stiffness in two different porcine cortical gray matter regions. While no significant difference was found between the two cortical regions, cortical gray matter was significantly less stiff than previously reported values of porcine thalamic gray matter (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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