Analyses of Fatal Cases of Kawasaki Disease in Japan Using Vital Statistical Data over 27 Years
| Autor: | Izumi Oki, Morihiro Tajimi, Ritei Uehara, Mayumi Yashiro, Masaru Terai, Hiroshi Yanagawa, Shinya Hayasaka, Toshiyuki Ojima, Yosikazu Nakamura |
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| Rok vydání: | 2003 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Time Factors Epidemiology Mucocutaneous Lymph Node Syndrome Sex Factors Japan Sex factors Case fatality rate medicine Humans Child Retrospective Studies business.industry Mortality rate Age Factors Infant Newborn Infant Mean age Retrospective cohort study General Medicine medicine.disease Vital Statistics Child Preschool Female Kawasaki disease business |
| Zdroj: | Journal of Epidemiology. 13:246-250 |
| ISSN: | 0917-5040 |
| Popis: | BACKGROUND: Chronological changes in mortality and case fatality rates from Kawasaki disease covering an extended period in Japan are still unknown. METHODS: We analyzed 679 deaths of patients in Japan whose underlying cause was Kawasaki disease, by using the data of vital statistics between 1972 and 1998. RESULTS: The male-to-female ratio of the number of deaths was 2.07 and the mean age at death in males was higher. Two unusual increases in the epidemic years, 1982 and 1986, were observed in the chronological changes of the number of deaths. The mortality rate of males was higher than that of females, with a few exceptional years, and the annual mortality rates were high in three epidemic years. The age-specific mortality rate was highest in infants under one year of age. Prefectures with high mortality rate clustered in some regions. The case fatality rate decreased annually, declining to as low as 0.2% among those who were born in 1986 and thereafter; and unusual increases in the case fatality rate affected by these three epidemic years were not repeated. CONCLUSIONS: The case fatality rate from Kawasaki disease in Japan decreased during the 27 years of observation: improvements in treatment might account for this. J Epidemiol 2003;13:246-250. |
| Databáze: | OpenAIRE |
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