Predictors of osteoradionecrosis following irradiated tooth extraction

Autor: Azizah Ahmad Fauzi, Siti Salmiah Mohd Yunus, Roszalina Ramli, Syed Nabil, Wei Cheong Ngeow, Szu Ching Khoo
Rok vydání: 2021
Předmět:
Adult
Male
Osteoradionecrosis
medicine.medical_treatment
R895-920
Mandibular canal
Dentistry
Medical physics. Medical radiology. Nuclear medicine
03 medical and health sciences
0302 clinical medicine
stomatognathic system
Risk Factors
Dental extraction
medicine
Humans
Radiology
Nuclear Medicine and imaging
RC254-282
Retrospective Studies
Univariate analysis
Predictors
business.industry
Research
Medical record
Extraction (chemistry)
Malaysia
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
030206 dentistry
Middle Aged
Prognosis
medicine.disease
Post radiotherapy
Radiation therapy
Mandibular Canal
stomatognathic diseases
medicine.anatomical_structure
Oncology
Head and Neck Neoplasms
030220 oncology & carcinogenesis
Tooth Extraction
Tooth pathology
Female
sense organs
business
Jaw Diseases
Zdroj: Radiation Oncology, Vol 16, Iss 1, Pp 1-12 (2021)
Radiation Oncology (London, England)
ISSN: 1748-717X
Popis: Background Tooth extraction post radiotherapy is one of the most important risk factors of osteoradionecrosis of the jawbones. The objective of this study was to determine the predictors of osteoradionecrosis (ORN) which were associated with a dental extraction post radiotherapy. Methods A retrospective analysis of medical records and dental panoramic tomogram (DPT) of patients with a history of head and neck radiotherapy who underwent dental extraction between August 2005 to October 2019 was conducted. Results Seventy-three patients fulfilled the inclusion criteria. 16 (21.9%) had ORN post dental extraction and 389 teeth were extracted. 33 sockets (8.5%) developed ORN. Univariate analyses showed significant associations with ORN for the following factors: tooth type, tooth pathology, surgical procedure, primary closure, target volume, total dose, timing of extraction post radiotherapy, bony changes at extraction site and visibility of lower and upper cortical line of mandibular canal. Using multivariate analysis, the odds of developing an ORN from a surgical procedure was 6.50 (CI 1.37–30.91, p = 0.02). Dental extraction of more than 5 years after radiotherapy and invisible upper cortical line of mandibular canal on the DPT have the odds of 0.06 (CI 0.01–0.25, p p = 0.01), respectively. Conclusion Extraction more than 5 years after radiotherapy, surgical removal procedure and invisible upper cortical line of mandibular canal on the DPT were the predictors of ORN.
Databáze: OpenAIRE
Externí odkaz: