Predictors of osteoradionecrosis following irradiated tooth extraction
Autor: | Azizah Ahmad Fauzi, Siti Salmiah Mohd Yunus, Roszalina Ramli, Syed Nabil, Wei Cheong Ngeow, Szu Ching Khoo |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male Osteoradionecrosis medicine.medical_treatment R895-920 Mandibular canal Dentistry Medical physics. Medical radiology. Nuclear medicine 03 medical and health sciences 0302 clinical medicine stomatognathic system Risk Factors Dental extraction medicine Humans Radiology Nuclear Medicine and imaging RC254-282 Retrospective Studies Univariate analysis Predictors business.industry Research Medical record Extraction (chemistry) Malaysia Neoplasms. Tumors. Oncology. Including cancer and carcinogens 030206 dentistry Middle Aged Prognosis medicine.disease Post radiotherapy Radiation therapy Mandibular Canal stomatognathic diseases medicine.anatomical_structure Oncology Head and Neck Neoplasms 030220 oncology & carcinogenesis Tooth Extraction Tooth pathology Female sense organs business Jaw Diseases |
Zdroj: | Radiation Oncology, Vol 16, Iss 1, Pp 1-12 (2021) Radiation Oncology (London, England) |
ISSN: | 1748-717X |
Popis: | Background Tooth extraction post radiotherapy is one of the most important risk factors of osteoradionecrosis of the jawbones. The objective of this study was to determine the predictors of osteoradionecrosis (ORN) which were associated with a dental extraction post radiotherapy. Methods A retrospective analysis of medical records and dental panoramic tomogram (DPT) of patients with a history of head and neck radiotherapy who underwent dental extraction between August 2005 to October 2019 was conducted. Results Seventy-three patients fulfilled the inclusion criteria. 16 (21.9%) had ORN post dental extraction and 389 teeth were extracted. 33 sockets (8.5%) developed ORN. Univariate analyses showed significant associations with ORN for the following factors: tooth type, tooth pathology, surgical procedure, primary closure, target volume, total dose, timing of extraction post radiotherapy, bony changes at extraction site and visibility of lower and upper cortical line of mandibular canal. Using multivariate analysis, the odds of developing an ORN from a surgical procedure was 6.50 (CI 1.37–30.91, p = 0.02). Dental extraction of more than 5 years after radiotherapy and invisible upper cortical line of mandibular canal on the DPT have the odds of 0.06 (CI 0.01–0.25, p p = 0.01), respectively. Conclusion Extraction more than 5 years after radiotherapy, surgical removal procedure and invisible upper cortical line of mandibular canal on the DPT were the predictors of ORN. |
Databáze: | OpenAIRE |
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