Antimicrobial activity of five essential oils from lamiaceae against multidrug-resistant Staphylococcus aureus
Autor: | Kamila Wierzchowska, Paweł Czerniewicz, M. Piechota, Grzegorz Chrzanowski, Barbara Kot |
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Rok vydání: | 2018 |
Předmět: |
Lavandula angustifolia
p-Cymene Traditional medicine 010405 organic chemistry Organic Chemistry Plant Science Biology Linalyl acetate Antimicrobial biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry Linalool Lamiaceae Menthol Thymol |
Zdroj: | Natural Product Research. 33:3587-3591 |
ISSN: | 1478-6427 1478-6419 |
DOI: | 10.1080/14786419.2018.1486314 |
Popis: | Analysis of Lamiaceae essential oils (EOs) by GC-FID-MS revealed the presence as the major constituents of linalool (16.8%), linalyl acetate (15.7%) in Lavandula angustifolia, menthol (29.0%), menthone (22.7%), menthyl acetate (19.2%) in Mentha x piperita, terpinen-4-ol (27.1%), (E)-sabinene hydrate (12.1%), γ-terpinene (10.0%) in Origanum majorana, α-thujone (19.5%), camphor (19.0%), viridiflorol (13.5%) in Salvia officinalis, thymol (61.9%), p-cymene (10.0%), γ-terpinene (10.0%) in Thymus vulgaris. Based on the MIC and MBC values (0.09–0.78 mg/mL) and ratio MBC/MIC showed that EO from T. vulgaris (TO) had the strong inhibitory and bactericidal effect against multidrug-resistant Staphylococcus aureus. The bacterial cells were total killed by TO at 2MIC concentration after 6 h. The higher concentrations of other EOs were needed to achieve bactericidal effects. The strong bactericidal effect of TO against these bacteria indicates the possibility of topical use of TO but it requires research under clinical conditions. |
Databáze: | OpenAIRE |
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