Epidemiology of ophthalmic lymphoma in Canada during 1992-2010
Autor: | Ivan V. Litvinov, Linda Moreau, Nebras Alghazawi, Elham Rahme, Feras M. Ghazawi, Miguel N. Burnier, Rami Darwich, Andrei Zubarev, Denis Sasseville |
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Rok vydání: | 2019 |
Předmět: |
Adult
Male medicine.medical_specialty Canada Adolescent Population Follicular lymphoma 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Age Distribution Epidemiology medicine Humans Registries Sex Distribution education Child Lymphoma Follicular Aged Aged 80 and over education.field_of_study Cancer prevention Geography business.industry Incidence (epidemiology) Eye Neoplasms Incidence Infant Newborn Cancer Infant Lymphoma B-Cell Marginal Zone Middle Aged medicine.disease Sensory Systems Cancer registry Ophthalmology 030220 oncology & carcinogenesis Child Preschool 030221 ophthalmology & optometry Female Lymphoma Large B-Cell Diffuse business Diffuse large B-cell lymphoma Demography |
Zdroj: | The British journal of ophthalmology. 104(8) |
ISSN: | 1468-2079 |
Popis: | BackgroundOphthalmic lymphoma (OL) is the most common orbital tumour, particularly in older individuals. Little is known about the epidemiology and geographic distribution of OL in Canada. Descriptive demographic statistics are an important first step in understanding OL burden and are necessary to inform comprehensive national cancer prevention programmes.MethodsWe determined patterns of incidence and geographical distribution of the three major subtypes of OL: extranodal marginal zone B cell lymphoma, follicular lymphoma (FL) and diffuse large B cell lymphoma. Here, we used cases that were diagnosed during 1992–2010 using two independent population-based cancer registries, the Canadian Cancer Registry and Le Registre Québécois du Cancer (LRQC).ResultsThe OL mean annual age-standardised incidence rate for 1992–2010 was 0.65 cases per million people per year with an average annual increase in the incidence rate of 4.5% per year. The mean age of diagnosis was 65 years. OL incidence rate was the highest in the cities located along the heavily industrialised Strait of Georgia in British Columbia.ConclusionsOur data on patient age, sex and temporal trends showed similarities with data reported in the USA and Denmark. Additional studies are needed to determine whether the observed increase in OL incidence is genuine or spurious. |
Databáze: | OpenAIRE |
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