Diabetes without Manifest Cardiovascular Disease: A Novel Approach in Risk Stratification and Treatment Selection
| Autor: | Rita Nemr, Samir Arnaout, Antoine Sarkis, Mounzer Saleh, Emile Andari, Elie Chammas, Sami T. Azar, Selim Jambart |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Consensus Endocrinology Diabetes and Metabolism Vascular complication Disease Type 2 diabetes 030204 cardiovascular system & hematology Protective Agents Asymptomatic Risk Assessment Glucagon-Like Peptide-1 Receptor 03 medical and health sciences 0302 clinical medicine Endocrinology Diabetes mellitus Internal medicine Medicine Humans Hypoglycemic Agents Mass Screening In patient 030212 general & internal medicine Sodium-Glucose Transporter 2 Inhibitors business.industry Patient Selection Cardiovascular Agents medicine.disease Coronary Vessels Diabetes Mellitus Type 2 Cardiovascular Diseases Risk stratification Calcium Risk of death medicine.symptom business Tomography X-Ray Computed Algorithms |
| Zdroj: | Current diabetes reviews. 16(8) |
| ISSN: | 1875-6417 |
| Popis: | Background: Cardiovascular disease (CVD), the main macro vascular complication of type 2 diabetes (T2D), increases the risk of death significantly in patients with T2D. Introduction: Most of the patients with T2D do not have obvious CVD symptoms. Due to the paucity of data, CVD screening in asymptomatic patients with T2D remains highly controversial. Methods: This has driven a panel of experts to establish a novel consensus on how to approach patients with T2D at high CVD risk. The panel formulated a stepwise algorithm by which patients with T2D undergo initial risk stratification into low, intermediate and high risk using the ASCVD calculator. In patients with intermediate risk, coronary artery calcium measurement is used to further stratify those patients into new low and high-risk categories. Results and Conclusion: The panel recommends using standard diabetes care in low risk patients and using SGLT2 inhibitors and GLP1 agonists with cardio protective effect, on top of standard care, in high risk individuals. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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