Efficacy of a virtual assistance-based lifestyle intervention in reducing risk factors for Type 2 diabetes in young employees in the information technology industry in India: LIMIT, a randomized controlled trial

Autor: Chittaranjan S. Yajnik, Dattatray S. Bhat, C. V. Joglekar, Kalyanaraman Kumaran, Tejas Limaye, R. Kulkarni, Arun S Nanivadekar
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Adult
Male
medicine.medical_specialty
Endocrinology
Diabetes and Metabolism

India
030209 endocrinology & metabolism
Type 2 diabetes
Overweight
law.invention
User-Computer Interface
03 medical and health sciences
0302 clinical medicine
Endocrinology
Randomized controlled trial
law
Intervention (counseling)
Glucose Intolerance
Internal Medicine
medicine
Humans
Obesity
030212 general & internal medicine
Occupational Health
Dyslipidemias
Hypertriglyceridemia
Text Messaging
Intention-to-treat analysis
Electronic Mail
business.industry
Cholesterol
HDL

Absolute risk reduction
Cholesterol
LDL

medicine.disease
Impaired fasting glucose
Diabetes Mellitus
Type 2

Hypertension
Physical therapy
Female
medicine.symptom
Information Technology
business
Reinforcement
Psychology

Risk Reduction Behavior
Cell Phone
Popis: Aims To investigate a virtual assistance-based lifestyle intervention to reduce risk factors for Type 2 diabetes in young employees in the information technology industry in India. Methods LIMIT (Lifestyle Modification in Information Technology) was a parallel-group, partially blinded, randomized controlled trial. Employees in the information technology industry with ≥3 risk factors (family history of cardiometabolic disease, overweight/obesity, high blood pressure, impaired fasting glucose, hypertriglyceridaemia, high LDL cholesterol and low HDL cholesterol) from two industrieswere randomized to a control or an intervention (1:1) group. After initial lifestyle advice, the intervention group additionally received reinforcement through mobile phone messages (three per week) and e-mails (two per week) for 1 year. The primary outcome was change in prevalence of overweight/obesity, analysed by intention to treat. Results Of 437 employees screened (mean age 36.2 ± 9.3 years; 74.8% men), 265 (61.0%) were eligible and randomized into the control (n=132) or intervention (n=133) group. After 1 year, the prevalence of overweight/obesity reduced by 6.0% in the intervention group and increased by 6.8% in the control group (risk difference 11.2%; 95% CI 1.2–21.1; P=0.042). There were also significant improvements in lifestyle measurements, waist circumference, and total and LDL cholesterol in the intervention group. The number-needed-to-treat to prevent one case of overweight/obesity in 1 year was 9 (95% CI 5–82), with an incremental cost of INR10665 (£112.30) per case treated/prevented. A total of 98% of participants found the intervention acceptable. Conclusions A virtual assistance-based lifestyle intervention was effective, cost-effective and acceptable in reducing risk factors for diabetes in young employees in the information technology industry, and is potentially scalable. This article is protected by copyright. All rights reserved.
Databáze: OpenAIRE