Tensile mechanical properties of the cervical, thoracic and lumbar porcine spinal meninges
| Autor: | Anthony Melot, Lucien Diotalevi, Nicolas Bailly, Éric Wagnac, Pierre-Jean Arnoux, Patrice Sudres, Yvan Petit, Morgane Evin |
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| Přispěvatelé: | Laboratoire de Biomécanique Appliquée (LBA UMR T24), Aix Marseille Université (AMU)-Université Gustave Eiffel |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cord
Swine Biomedical Engineering 02 engineering and technology Biomaterials 03 medical and health sciences 0302 clinical medicine Lumbar Meninges Elastic Modulus medicine Animals Spinal canal Spinal Meninges ComputingMilieux_MISCELLANEOUS Pia mater business.industry Biomechanics 030206 dentistry Anatomy [SPI.MECA]Engineering Sciences [physics]/Mechanics [physics.med-ph] 021001 nanoscience & nanotechnology Spinal cord medicine.anatomical_structure Spinal Cord Mechanics of Materials Pia Mater Dura Mater Stress Mechanical 0210 nano-technology business |
| Zdroj: | Journal of the mechanical behavior of biomedical materials Journal of the mechanical behavior of biomedical materials, 2021, 115 (4), pp.104280. ⟨10.1016/j.jmbbm.2020.104280⟩ Journal of the mechanical behavior of biomedical materials, Elsevier, 2021, 115, pp.104280. ⟨10.1016/j.jmbbm.2020.104280⟩ |
| ISSN: | 1751-6161 1878-0180 |
| DOI: | 10.1016/j.jmbbm.2020.104280⟩ |
| Popis: | Background The spinal meninges play a mechanical protective role for the spinal cord. Better knowledge of the mechanical behavior of these tissues wrapping the cord is required to accurately model the stress and strain fields of the spinal cord during physiological or traumatic motions. Then, the mechanical properties of meninges along the spinal canal are not well documented. The aim of this study was to quantify the elastic meningeal mechanical properties along the porcine spinal cord in both the longitudinal direction and in the circumferential directions for the dura-arachnoid maters complex (DAC) and solely in the longitudinal direction for the pia mater. This analysis was completed in providing a range of isotropic hyperelastic coefficients to take into account the toe region. Methods Six complete spines (C0 – L5) were harvested from pigs (2–3 months) weighing 43±13 kg. The mechanical tests were performed within 12 h post mortem. A preload of 0.5 N was applied to the pia mater and of 2 N to the DAC samples, followed by 30 preconditioning cycles. Specimens were then loaded to failure at the same strain rate 0.2 mm/s (approximately 0.02/s, traction velocity/length of the sample) up to 12 mm of displacement. Results The following mean values were proposed for the elastic moduli of the spinal meninges. Longitudinal DAC elastic moduli: 22.4 MPa in cervical, 38.1 MPa in thoracic and 36.6 MPa in lumbar spinal levels; circumferential DAC elastic moduli: 20.6 MPa in cervical, 21.2 MPa in thoracic and 12.2 MPa in lumbar spinal levels; and longitudinal pia mater elastic moduli: 18.4 MPa in cervical, 17.2 MPa in thoracic and 19.6 MPa in lumbar spinal levels. Discussion The variety of mechanical properties of the spinal meninges suggests that it cannot be regarded as a homogenous structure along the whole length of the spinal cord. |
| Databáze: | OpenAIRE |
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