Monitoring deep inspiration breath hold for left-sided localized breast cancer radiotherapy with an in-house developed laser distance meter system
| Autor: | Christer André Jensen, Jo-Åsmund Lund, Tatiana Mikhailovna Abramova, Jomar Frengen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Systematic error
Organs at Risk medicine.medical_specialty laser distance measurer medicine.medical_treatment 87.55.Qr Anterior Descending Coronary Artery Breast cancer radiotherapy Mastectomy Segmental Left sided 030218 nuclear medicine & medical imaging Breath Holding 03 medical and health sciences 0302 clinical medicine Breast cancer medicine Unilateral Breast Neoplasms Radiation Oncology Physics Humans Radiology Nuclear Medicine and imaging Instrumentation Lung Deep inspiration breath-hold Reproducibility Radiation business.industry Radiotherapy Planning Computer-Assisted DIBH Reproducibility of Results Heart medicine.disease Surgery Radiation therapy 87.55.ne respiratory gating Inhalation 030220 oncology & carcinogenesis 87.55.tg Female breast cancer radiation therapy Nuclear medicine business Tomography X-Ray Computed |
| Zdroj: | Journal of Applied Clinical Medical Physics |
| Popis: | Deep inspiration breath hold (DIBH) in left‐sided breast cancer radiotherapy is a technique to reduce cardiac and pulmonary doses while maintaining target coverage. This study aims at evaluating an in‐house developed DIBH system. Free‐breathing (FB) and DIBH plans were generated for 22 left‐sided localized breast cancer patients who had radiation therapy (RT) after breast‐conserving surgery. All patients were treated utilizing an in‐house laser distance measuring system. 50 Gy was prescribed, and parameters of interest were target coverage, left anterior descending coronary artery, (LAD) and heart doses. Portal images were acquired and the reproducibility and stability of DIBH treatment were compared to FB. The comparing result shows there is a significant reduction in all LAD and heart dose statistics for DIBH compared to FB plans without compromising the target coverage. The maximum LAD dose was reduced from 43.7 Gy to 29.0 Gy and the volume of the heart receiving >25 Gy was reduced from 3.3% to 1.0% using the in‐house system, both statistically significant. The in‐house system gave a reproducible and stable DIBH treatment where the systematic error ∑, and random error σ, were less than 2.2 mm in all directions, but were not significantly better than at FB. The system was well tolerated and all patients completed their treatment sessions with DIBH. © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|